Subject(s)
Ectoparasitic Infestations/diagnosis , Foot Dermatoses/microbiology , Foot Dermatoses/parasitology , Insecta , Nail Diseases/microbiology , Nail Diseases/parasitology , Onychomycosis/diagnosis , Trichophyton/isolation & purification , Adult , Animals , Diagnosis, Differential , Ectoparasitic Infestations/parasitology , Humans , Male , Onychomycosis/microbiologyABSTRACT
On the basis of a case of their own, the authors report on the evolution of a rhinophyma. Therapeutic results obtained with conservative treatment were not satisfactory. In contrast, a combination of surgical removal of the skin changes and systematic treatment with isotretinoin was associated with good results. Contraindications and possible side effects must always be borne in mind.
Subject(s)
Rhinophyma/surgery , Rhinoplasty/methods , Combined Modality Therapy , Follow-Up Studies , Humans , Isotretinoin/administration & dosage , Male , Middle Aged , Rhinophyma/drug therapyABSTRACT
Based on a case of our own observation, we present the characteristic features of a rare skin disease: hyperkeratosis follicularis et parafollicularis in cutem penetrans, i.e. Kyrle's disease. The clinical picture shows follicular and interfollicular hyperkeratotic horn-like plugs with a typical distribution pattern. The classical histological features are epidermolysis and hyperkeratoses advancing towards the dermis. Today, this disease is regarded as a genodermatosis with recessive heredity and is best treated with systemic and topical application, resp., of vitamin A acid.