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1.
Rev Med Chir Soc Med Nat Iasi ; 105(3): 457-61, 2001.
Article in Romanian | MEDLINE | ID: mdl-12092173

ABSTRACT

The anormalous origin of the left coronary artery from pulmonary artery (White-Bland Garland syndrome) is a very rare coronary malformation, having despite the great mortality in the early childhood, an adult form, characterized by minor symptoms and long course. This paradoxical situation is totally dependant to the complete development of the coronary anastomosis, allowing the right coronary flow to perfuse the left myocardium. The theory of the "terminal arterial perfusion" of the heart, still persistent in some monographs is meeting in this natural situation its strongest opponent argumentation. The coronary anastomosis, clearly visible by coronarography are large enough (in late stages) to inverse the flow in left coronary artery, filling the pulmonary artery. Is the coronary-pulmonary shunt, responsible for the majority of symptoms, in the 5th or 6th decade. The adult form of the White-Bland Garland syndrome is indicative for the maximum result we may hope to reach using the new revascularisation method for ischemic heart disease: new vessels formation and enhancing the coronary anastomosis by growth factors administration therapy.


Subject(s)
Coronary Circulation/physiology , Coronary Vessel Anomalies/physiopathology , Adult , Coronary Vessel Anomalies/pathology , Electrocardiography , Humans , Infant , Pulmonary Artery/abnormalities , Syndrome
2.
Rev Med Chir Soc Med Nat Iasi ; 105(4): 677-81, 2001.
Article in Romanian | MEDLINE | ID: mdl-12092219

ABSTRACT

The anomalous origin of the left coronary artery from pulmonary artery (White-Bland-Garland syndrome) is a very rare coronary malformation, having despite the great mortality in the early childhood, an adult form, characterized by minor symptoms and long course. This paradoxical situation is totally dependent to the complete development of the coronary anastomosis, allowing the right coronary flow to perfuse the left myocardium. The theory of the "terminal arterial perfusion" of the heart, still persistent in some monographs is meeting in this natural situation its strongest opponent argumentation. The coronary anastomosis, clearly visible by coronarography are large enough (in late stages) to inverse the flow in left coronary artery, filling the pulmonary artery. Is the coronary-pulmonary shunt, responsible for the majority of symptoms, in the 5th or 6th decades. The adult form of the White-Bland-Garland syndrome is indicative for the maximum result we may hope to reach using the new revascularisation method for ischemic heart disease: new vessels formation and enhancing the coronary anastomosis by growth factors administration therapy.


Subject(s)
Coronary Vessel Anomalies/pathology , Pulmonary Artery/abnormalities , Coronary Artery Bypass/methods , Coronary Circulation/physiology , Coronary Vessel Anomalies/diagnostic imaging , Coronary Vessel Anomalies/surgery , Humans , Pulmonary Artery/diagnostic imaging , Pulmonary Artery/surgery , Radiography , Syndrome
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