ABSTRACT
A 49-year-old woman treated with increasing dosage of propylthiouracil (PTU) in order to control hyperthyroidism, developed progressive necrotic ulcers in the oral cavity, oropharynx and rhinopharynx and vasculitic ulcers on both auricular pinnae after a few days. The PTU treatment was immediately discontinued and the mucosal and skin manifestations resolved promptly. Laboratory findings, including anti-neutrophil cytoplasmic antibodies (ANCA), suggested allergic vasculitis. This is to our knowledge the first reported case of oral manifestations of PTU-induced allergic vasculitis.
Subject(s)
Antibodies, Antineutrophil Cytoplasmic/blood , Antithyroid Agents/adverse effects , Propylthiouracil/adverse effects , Vasculitis, Leukocytoclastic, Cutaneous/chemically induced , Female , Humans , Middle Aged , Oral Ulcer/chemically inducedABSTRACT
A material of 286 patients or 545 ears submitted to operation for protruding ears operated by Stenströms and Nordzells surgical procedure over a period of ten years were reviewed retrospectively. One hundred and sixty-three patients were clinically investigated and interviewed. The mean observation time was eight years. Satisfactory results were obtained in 94% of the patients subjectively. Objectively there was a good result in 74% of the cases. Relatively few complications and reoperations occurred. However 20% of the patients interviewed had postoperative pain more than one year after the operation. The results of the operations are reviewed and discussed. There was no significant difference between the results of the surgical procedure a.m. Stenström and a.m. Nordzell.
Subject(s)
Ear, External/surgery , Otologic Surgical Procedures/methods , Plastic Surgery Procedures/methods , Adolescent , Adult , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Otologic Surgical Procedures/adverse effects , Pain, Postoperative/diagnosis , Plastic Surgery Procedures/adverse effects , ReoperationABSTRACT
Ranula is a cystic swelling of the floor of the mouth, which is usually unilateral and relatively uncommon. The cyst arises from the sublingual salivary gland. We reviewed 14 patients operated in the period 1976-April 1998. There was no recurrence after marsupialization and after extirpation of the sublingual gland. Fourteen percent of the patients had recurrence after extirpation of the cyst. At the follow-up time (average 8.1 years) 18.2% had complications. We suggest that marsupialization/extirpation of the cyst should be primary treatment. In case of recurrence the sublingual gland should be extirpated.
Subject(s)
Mouth Diseases/surgery , Ranula/surgery , Adolescent , Adult , Child , Child, Preschool , Female , Follow-Up Studies , Humans , Male , Middle Aged , Recurrence , Sublingual Gland/surgeryABSTRACT
A twenty-year old woman was admitted to hospital with impaired consciousness and a left hemiparesis. A cerebral CAT-scanning was reported normal. Convulsions and respiratory insufficiency made intubation and mechanical ventilation necessary. Laboratory examination showed an extremely low concentration of albumin in plasma (109 microM) and gross albuminuria was present. No other signs of renal failure occurred. The patient deteriorated during three days and died with signs of cerebral incarceration, despite efforts to reduce intracranial pressure. Autopsy showed a large thrombus of the sagittal sinus as the presumed cause of death. No thrombus was found in the renal vein. The association between nephrotic syndrome and thrombosis is discussed.
