ABSTRACT
A radiologic and tomographic study was made of the cranioencephalic topography of canary goats of medium weight and size. In a first step, the exocranialis references corresponding to an axis designed at the level of the meatus acusticus externus and parallel to the basicranial axis were anatomically and radiologically defined. Conventional stereotaxic techniques were then used to reach the standard position of the head in order to obtain macroscopical cross sections at different levels perpendicular to the base of the cranium. In a second step, a tomographic study was made to confirm the design of the axis.
Subject(s)
Brain/anatomy & histology , Brain/diagnostic imaging , Goats/anatomy & histology , Skull/anatomy & histology , Skull/diagnostic imaging , Animals , Tomography, X-Ray Computed/veterinaryABSTRACT
Inducibility of NADPH-diaphorase (NADPH-d) or nitric oxide synthase (NOS) has been demonstrated in pyramidal neurones of the hippocampus, but the mechanisms of this induction are not known. The present study aimed to assess the role of anti-inflammatory drugs in injury-induced production of NADPH-d/NOS in CA1 pyramidal neurones. We found that either a steroid, dexamethasone or a non-steroid, indomethacin, prevents induction of these enzymes. We also found that NO is not necessary for the induction. None of the three drugs used had detectable effect on the neurones which contain constitutive NADPH-d/NOS.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Anti-Inflammatory Agents/pharmacology , Brain Injuries/enzymology , NADPH Dehydrogenase/biosynthesis , Pyramidal Cells/enzymology , Animals , Arginine/analogs & derivatives , Arginine/pharmacology , Dexamethasone/pharmacology , Enzyme Induction/drug effects , Hippocampus/cytology , Hippocampus/drug effects , Hippocampus/injuries , Indomethacin/pharmacology , NG-Nitroarginine Methyl Ester , Nitric Oxide/antagonists & inhibitors , Pyramidal Cells/drug effects , Rats , Rats, Sprague-DawleyABSTRACT
Se realiza la revisión de 115 expedientes clinicos del hospital psiquiatrico de luanda en un semestre. Se estudian 106 pacientes que presentaron sintomas y signos psiquiatricos en el curso del paludismo a P. Falciparum. Se hace referencia a la presentacion o signologia predominante de la enfemedead. Finalmente se exponen la regresión total de los síntomas y signos de referencia como respuesta efectiva al tratamiento antimalarico habitual
