Extraintestinal oxyuriasis - report of three cases and review of literature.

Extraintestinal oxyuriasis, in our experience with three affected women of fertile age, presented itself as a solitary fibrotic nodular lesion, with a varying location. The sites of location were: parietal peritoneum, serous surface of the uterus and wall of the uterine tube. The size of the nodules was 5 to 10 mm. Histologically, the lesions were hypocellular fibrotic nodules with a variable amount of neutrophils and amorphous eosinophilic material in the center, harbouring eggs of the parasite and remnants of pinworm cuticle. All three lesions were asymptomatic, only being discovered incidentally during the operations for unrelated conditions. Their peroperative recovery by a surgeon did not alter the course of surgery. These findings document the ability of pinworms to migrate into the abdominal cavity via the female genital tract.

Poorly differentiated endocrine carcinoma and intraductal papillary-mucinous neoplasm of the pancreas: Description of an unusual case.

Neuroendocrine tumors and intraductal papillary-mucinous neoplasms constitute histologically distinctive but relatively rare entities among pancreatic tumors. Collision of these tumors is extremely rare and causes several diagnostic problems regarding the histopathologic differential diagnosis of other pancreatic epithelial tumors. The question of whether the neoplastic populations originate from common progenitor cell or whether they represent only a fortuitous association has not been sufficiently explained. Here, we describe a new case of poorly differentiated endocrine carcinoma combined with an intraductal papillary-mucinous neoplasm. To disclose the relationship between the two histologic components, neuroendocrine differentiation was studied by confocal laser scanning microscopy using double immunofluorescence labeling with chromogranin-A and CD57 antibodies. Our results revealed a co-localization of both antigens in neuroendocrine cells of the intraductal papillary-mucinous neoplasm. The finding has previously been described in non-neoplastic neuroendocrine cells. Cells forming poorly differentiated endocrine carcinoma showed a wide heterogeneity in immunoreactions. Our results do not indicate a potential histogenetic similarity between these two neoplasms, which are dissimilar histologically, and underline the previous thesis that cells in intraductal papillary-mucinous neoplasm revealing neuroendocrine differentiation represent only a non-neoplastic cell admixture.

Guided tissue regeneration, barrier membranes and reconstruction of the cleft maxillary alveolus.

The use of barrier membranes for bone regeneration is especially beneficial in the case of severely affected soft tissue. One useful indication may be the formation of an effective shell for bone grafts in maxilla cleft defect reconstruction. When selecting a proper material for clinical use, one must consider the safety record, the resorption time and route of elimination, the time of the maintained barrier function, the necessary time of mechanical strength, and costs. Two resorbable collagen membranes, one of single-layer and one of double-layer material, were tested in vitro and in vivo. The tested single-layer membrane is less expensive, but it is also less handling than the double-layer membrane. In vitro, samples were incubated in simulated surgical wound. A complete unambiguous picture of disintegration was not proved histologically in either material in six investigation terms (1-6 weeks). In vivo the effect of the assessed membranes was verified on a group of patients (N = 45) with a cleft. Materials were applied in the reconstruction of the alveolar defect by cancellous bone grafts. The influence on the course of healing was not stated as statistically significant. However, with respect to the costs of double layer membrane, this material was used in the most severe cases.

Moustache reconstruction in patients with cleft lip: (final aesthetic touches in clefts-part ii).

Men with clefts often have limited or even missing moustache growth in scar areas or in the upper lip prolabium. However the histological testing showed the absence or at least the inactive form of androgenic receptor in hair follicle of cleft site, transplantation of autologous grafts harvested from hair was successful in all six cases either into scars or the prolabium. A more natural effect was achieved by using micrografts. The positive reaction of patients proved there is a need for detailed treatment in highly outgoing individuals.

[Liposarcoma of the spermatic cord]. / Liposarcome du cordon spermatique.

Liposarcoma of the spermatic cord is rare. It usually presents as a painless slowly-growing scrotal mass of consistency like lipoma. Inguinal orchiectomy is an adequate surgical approach. Retroperitoneal lymphadenectomy is not indicated owing to the low malignancy potential of the sarcomas. Value of adjuvant radiotherapy/chemotherapy remains uncertain. Recurrences are frequent, owing to incomplete surgical removal of the tumor. We report on a 62 year old male who presented with a half a year history of a soft painless mass in the left scrotum extending from the groin up to the testis. Clinical examination suggested inguinal hernia. Radical orchiectomy was performed. Histological examination revealed a well-differentiated liposarcoma of sclerosing subtype. No evidence of recurrence or metastases has been noted during the 6-month and one year follow-up without any postoperative adjuvant therapy.

The role of bone scan in the diagnosis of Jaffé-Lichtenstein-Uehlinger syndrome.

The case of a 12-year-old girl with Jaffé-Lichtenstein-Uehlinger syndrome is presented. A bone scan pattern exhibits clinical symptoms, X ray images and histological findings are described in a case of polyostotic form of the fibrous dysplasia. A biopsy with histology was performed in consideration of bone scan findings and a confirmed final diagnosis.