ABSTRACT
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Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Cysticercosis/diagnosis , Cysticercosis/drug therapy , Cysticercosis/surgery , Surgery, Oral/methods , Mucocele/diagnosis , Mucocele/therapy , Diagnosis, Differential , Cysticercus , Cysticercus/isolation & purification , Mouth/pathology , Mouth/surgery , Lipoma/complications , Lipoma/diagnosis , Taenia solium/isolation & purificationABSTRACT
Numerous efforts for the development of basic and clinical research in obesity are being made by the National Institutes of Health and Federal Reference Hospitals in Mexico. However, greater interaction among researchers and stronger efforts towards the dissemination of the results are needed. The document outlines the general ideas and proposals of the Academic Group for the Study, Prevention and Treatment of Obesity and Metabolic Syndrome of the Coordinating Committee of the National Institutes of Health and High Specialty Hospitals (CCINSHAE). This is the first step in developing common objectives, with the aim of understanding the effect of these entities in public health and to establish guidelines to limit and eventually overcome them. We discuss the appropriateness of analyzing obesity and the metabolic syndrome together, and the current management of these entities at the National Institutes of Health in Mexico. The problems that arise in clinical practice lead to the need to generate a new model of medical care, including a new health worker and a new patient. It is imperative to establish permanent lines of communication and education with health personnel and with patients. The group proposes an integrated approach for research in these areas. Finally, a master plan that links the National Institutes of Health, particularly in the areas of research and programs within the institutions, is required as a first step in seeking answers useful in solving the problem. The second step would be linking the first and second levels of care through concrete actions needed to limit and reduce obesity and metabolic syndrome in the population.
Subject(s)
Metabolic Syndrome , Obesity , Government Agencies , Humans , Metabolic Syndrome/epidemiology , Metabolic Syndrome/prevention & control , Mexico , Obesity/epidemiology , Obesity/prevention & controlSubject(s)
Cerebrovascular Circulation/immunology , Cerebrovascular Disorders/cerebrospinal fluid , Cerebrovascular Disorders/physiopathology , Cytokines/cerebrospinal fluid , Neurocysticercosis/cerebrospinal fluid , Neurocysticercosis/physiopathology , Adult , Aged , Anti-Inflammatory Agents/therapeutic use , Antiparasitic Agents/therapeutic use , Biomarkers/cerebrospinal fluid , Cerebral Arteries/diagnostic imaging , Cerebral Arteries/physiopathology , Chemokine CCL5/analysis , Chemokine CCL5/cerebrospinal fluid , Female , Humans , Interleukin-1beta/analysis , Interleukin-1beta/cerebrospinal fluid , Interleukin-6/analysis , Interleukin-6/cerebrospinal fluid , Magnetic Resonance Imaging , Male , Middle Aged , Neurocysticercosis/drug therapy , Tomography, X-Ray Computed , Treatment Outcome , Tumor Necrosis Factor-alpha/analysis , Tumor Necrosis Factor-alpha/cerebrospinal fluid , Ultrasonography, Doppler, TranscranialSubject(s)
Health Facilities/history , Neurology , Neurosurgery , Mexico , Public Health/history , History of MedicineABSTRACT
Una secuela frecuente secundaria a cisticercosis en el parénquima cerebral es el granuloma calcificado. En la mayoría de los pacientes, la única manifestación clínica es epilepsia, frecuentemente en forma de crisis parciales. El granuloma parenquimatoso cerebral es una pequeña lesión no progresiva y bien definida fácilmente detectable por tomografía computarizada. En este estudio seleccionamos 149 pacientes con granuloma cerebral único y crisis epilépticas parciales. Aunque en general la manifestación de epilepsia se encontró de acuerdo a la tomografía de la lesión cerebral, algunos hallazgos en pacientes no están de acuerdo con conceptos clásicos de localización cerebral en epilepsia y apoyan datos recientes que demuestran amplias variaciones individuales. En base a nuestras observaciones, proponemos el estudio de pacientes con epilepsia secundaria a un granuloma parenquimatoso, secuela de cisticerco como un modelo para análisis de los mecanismos fisiopatológicos de la epilepsia.