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1.
J Trop Pediatr ; 45(4): 215-20, 1999 08.
Article in English | MEDLINE | ID: mdl-10467832

ABSTRACT

We evaluated helminthic infection and anthropometric indicators of nutritional status in a group of school-age children from a slum area of Caracas, Venezuela. The proportions of children at or below the 10th percentiles for height/age and weight/age were significantly higher in those presenting helminthiasis than in those uninfected. Although this could partially reflect a codependence of both helminthic infection and undernutrition or poverty, when the children were administered regular anthelmintic treatment for a year their anthropometric values improved significantly. When they were re-evaluated 8 months after the end of anthelmintic administration, the degree of reinfection by the most common helminth, Ascaris lumbricoides, was significantly higher in the growth-retarded children. These results confirm the relationship between helminthic infection and decreased growth rates in underprivileged populations, and indicate that children at nutritional risk are more susceptible to such infections, even after a prolonged parasite-free period.


Subject(s)
Anthelmintics/therapeutic use , Helminthiasis/drug therapy , Nutrition Disorders/prevention & control , Poverty Areas , Anthropometry , Child , Follow-Up Studies , Helminthiasis/complications , Helminthiasis/epidemiology , Humans , Nutrition Disorders/epidemiology , Nutrition Disorders/etiology , Recurrence , Venezuela/epidemiology
2.
In. Bianco, Nicolas; Machado, Irma. Inmunología clínica, 89. s.l, Fondo Editorial CONICIT, 1989. p.237-41, tab.
Monography in Spanish | LILACS | ID: lil-95343

ABSTRACT

Las enfermedades diarreicas están difundidas y causan todos los años la muerte de más de 4,5 millones de menores de 5 años, la importancia que presentan los rotavirus como agentes virales ha originado que se desarrollen estrategias inmunoprofilácticas, siendo de ellas la utilizadas en el desarrollo de una vacuna anti-rotavirus que consisten en el uso de una cepa animal relacionada antigenicamente y que sea capaz de crecer de manera eficiente en cultivos celulares. En este estudio fueron seleccionados 54 niños con edades entre 4 y 10 meses y recibieron 2 dosis de vacunas y el placebo. Fueron tomadas muestras de heces diariamente durante el período de observación. Los resultados preliminares de este estudio demostraron que la vacuna no produce reacciones secundarias en los diferentes grupos etarios estudiados, en especial en el grupo menor de 4 meses, en el grupo de niños de 2 a 3 meses se determinó la excreción viral en un 75


Subject(s)
Infant , Child , Humans , Male , Female , Feces/analysis , Rotavirus/drug effects , Viral Vaccines/immunology
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