[A model of audiogenic epilepsy--rats of the Krushinskii-Molodkina strain. Proof of genetic homogeneity]. / Model' audiogennoi épilepsii--krysy linii Krushinskogo--Molodkinoi. Dokazatel'stvo geneticheskoi odnorodnosti.

Genetical homogeneity of Krushinskii-Molodkina (KM) stock was studied by the method of reciprocal transplantation of skin. The rats were selected inside genealogic card from 5 different substrains of the 20th generation of brother-sister crossing (F 20). The tail-to-tail transplantation was made by the scheme of double reciprocal ring in 9 females from the KM stock. Observations within 314 days showed a good condition of the transplants. The obtained data suggest that Krushinskii-Molodkina rats are an inbred strain.

[The protective action of different types and regimens of adaptation to hypoxia on the development of stress-induced lesions in KM strain (Krushinskii-Molodkina) rats]. / Protektornoe deistvie raznykh vidov i rezhimov adaptasii k gipoksii na razvitie stressovykh povrezhdenii u krys linii KM.

The effect of preliminary adaptation to hypoxia on the development of stress-induced lesions was studied on the model of acoustic stress in the Krushinskii-Molodkina line rats genetically predisposed to audiogenic seizures. At different regimens of adaptation to hypoxia (long- and short-term, continuous, intermittent), a decrease of the death rate, severity of motor disorders, incidence and degree of intracranial hemorrhages occurred. Only when using a hypoxic gas mixture, a reduction of excitability of the c.n.s. was revealed: the latency increased whereas the intensity of the seizure decreased. Two-hour normobaric hypoxic stimulation prevented an increase in the lipid peroxidation products and contributed to a rise of cyclic nucleotides concentration in the brain hemispheres of the KM line rats exposed to acoustic stress.

[Effect of short-term adaptation to hypoxia on the development of acute cerebral circulatory disorders in rats genetically disposed to epilepsy]. / Vliianie kratkovremennoi adaptatsii k gipoksii na razvitie ostrykh narushenii mozgovogo krovoobrashcheniia u krys, geneticheski predraspolozhennykh k épilepsii.

The exposure of KM rats genetically predisposed to autogenic convulsive fits, to hypobaric hypoxia had a protective effect on the extension of cerebrovascular disorders in conditions of acoustic stress, reducing the severity of motor disorders and the degree of intracranial hemorrhage (subdural, subarachnoidal, intraventricular).

[Effect of animal rearing conditions on their ability to solve extrapolation problems]. / Vliianie uslovii vyrashchivaniia zhivotnykh na ikh sposobnost' k resheniiu ékstrapoliatsionnoi zadachi.

The ability for elementary rational activity (Krushinsky, 1977) was analysed in various animals (crows, foxes, cats, rats). The animals raised in "enriched" environment solved an extrapolation problem as successfully as those raised in "impoverished" environment. The question requires further investigation.