1.
Chem Commun (Camb)
; 48(90): 11145-7, 2012 Nov 21.
Article
in English
| MEDLINE
| ID: mdl-23045242
ABSTRACT
An efficient route to 4-aryl-2-naphthols from arynes and aroylacetones was developed by carbon-carbon bond insertion followed by an intramolecular aldol reaction and dehydration. Benzyne derived from 2-(trimethylsilyl)phenyl triflate reacted with benzoylacetones in refluxing acetonitrile to give 4-aryl-2-naphthols and 3-aryl-1-naphthols.