ABSTRACT
Pemphigus foliaceus is a chronic autoimmune disease of the skin, clinically characterized by scaly and crusty cutaneous erosions involving the seborrheic areas. The patient can eventually become erythrodermic. There are reports of atypical cases of pemphigus foliaceus with pustules and neutrophils, and clinical differentiation from generalized pustular psoriasis of von Zumbusch is difficult. We report the case of a 55-year-old man with a history of psoriasis vulgaris that has developed pemphigus foliaceus with pustules, triggered by withdrawal of systemic corticosteroids. This is the first report associating this atypical form of pemphigus with psoriasis, suggesting that an overlap with generalized pustular psoriasis can occur.
Subject(s)
Pemphigus/etiology , Pemphigus/pathology , Psoriasis/complications , Psoriasis/pathology , Biopsy , Dose-Response Relationship, Drug , Erythema/pathology , Glucocorticoids/therapeutic use , Humans , Male , Middle Aged , Pemphigus/drug therapy , Prednisone/therapeutic use , Psoriasis/drug therapy , Skin/pathologyABSTRACT
Abstract Pemphigus foliaceus is a chronic autoimmune disease of the skin, clinically characterized by scaly and crusty cutaneous erosions involving the seborrheic areas. The patient can eventually become erythrodermic. There are reports of atypical cases of pemphigus foliaceus with pustules and neutrophils, and clinical differentiation from generalized pustular psoriasis of von Zumbusch is difficult. We report the case of a 55-year-old man with a history of psoriasis vulgaris that has developed pemphigus foliaceus with pustules, triggered by withdrawal of systemic corticosteroids. This is the first report associating this atypical form of pemphigus with psoriasis, suggesting that an overlap with generalized pustular psoriasis can occur.
Subject(s)
Humans , Male , Middle Aged , Psoriasis/complications , Psoriasis/pathology , Pemphigus/etiology , Pemphigus/pathology , Psoriasis/drug therapy , Skin/pathology , Biopsy , Prednisone/therapeutic use , Pemphigus/drug therapy , Dose-Response Relationship, Drug , Glucocorticoids/therapeutic useABSTRACT
Retalhos cutâneos constituem técnica cirúrgica particularmente útil para reparos estéticos nos casos de excisões extensas e/ou lesões de localizações peculiares, como a orelha. Diversas opções de retalhos cutâneos já foram descritas, determinando resultados variáveis que dependem do conhecimento teórico e da experiência prática do cirurgião. O objetivo deste artigo é relatar dois casos de sucesso com a utilização das técnicas de retalhos anterior e posterior para reparação da orelha e revisar a literatura afim.
The skin flaps are surgical techniques particularly useful to aesthetic repair in cases of extended excision and/or unusual sites, as in the ear. Many skin flaps options were already reported, resulting in variable results of the theoretical knowledge and practical experience of the surgeon. This article aims to describe two successful cases of ear reconstruction with the use of anterior and posterior flaps and to review the current literature.