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J Microencapsul ; 17(1): 111-6, 2000.
Article in English | MEDLINE | ID: mdl-10670944

ABSTRACT

Polyurethanes and polyvinyl alcohol modified by stearyl isocyanate are used as a matrix for microparticles made by a solvent evaporation process to encapsulate allergenic molecules, with petrolatum used as a neutral vehicle. The encapsulation yields, depending on the agent to be encapsulated, vary from 22 to 45%.


Subject(s)
Allergens/administration & dosage , Capsules/chemical synthesis , Dermatitis, Contact/diagnosis , Drug Compounding/methods , Skin Tests , Allergens/immunology , Benzocaine/administration & dosage , Benzocaine/immunology , Benzocaine/metabolism , Capsules/chemistry , Capsules/metabolism , Chemistry, Pharmaceutical , Cyanates , Dermatitis, Contact/immunology , Drug Stability , Drug Storage , Humans , Methanol/metabolism , Microscopy, Electron, Scanning , Petrolatum , Polyurethanes/chemistry , Polyvinyl Alcohol/analogs & derivatives , Polyvinyl Alcohol/chemistry , Solubility , Solutions , Solvents , Spectrophotometry, Ultraviolet , Water/metabolism
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