ABSTRACT
McArdle's disease, known as blockage of muscle glycogen metabolism, is characterized by glycogen accumulation of chains in skeletal striated muscles. One of the typical symptoms of the disease is the feeling of intolerance to exercise. Severe muscle cram and contracture, which often cause stiffness, occur due to a lack of muscle energy substrate during the exercise. These factors can lead to muscle damage, myoglobinuria, and, in severe cases, renal failure and rhabdomyolysis. Rhabdomyolysis is a syndrome that presents injury and necrosis of muscle cells leading to the release of intracellular material to the circulatory system. The present study aimed to report rhabdomyolysis in an individual with McArdle's disease after exercise of walking with low intensity. Patient, aged 33 years, was treated in the emergency room of a hospital located in the State of Rio de Janeiro, Brazil. After performing a full lap on the block of home (~500 m in ~4 min 37 s), walking at a moderate speed (~6.5 km/h), the individual felt sick and was rescued, later being hospitalized. The examinations collected presented hematocrit (HCT) compatible with chronic disease anemia and myoglobinuria. The patient was discharged from the intensive care center on the 3rd day, after a 45% drop in creatine kinase. The patient described in the present study achieved full recovery. Attention to symptoms, early diagnosis, and immediate treatment made it possible to interrupt the development of complications caused by rhabdomyolysis, not allowing progression to acute renal failure.
Subject(s)
Glycogen Storage Disease Type V , Myoglobinuria , Rhabdomyolysis , Humans , Glycogen Storage Disease Type V/complications , Glycogen Storage Disease Type V/diagnosis , Glycogen Storage Disease Type V/therapy , Brazil , Rhabdomyolysis/diagnosis , Rhabdomyolysis/etiology , Rhabdomyolysis/therapy , Exercise , GlycogenABSTRACT
Introduction: The training routine planned, and performed correctly results in exercises that, systematically organized,influence the levels of strength, and muscle hypertrophy. However, the magnitudes of these gains vary considerably. Tooptimize these gains, it is important to underst, and the interaction between training variables such as external load, volume,number of exercises, number of repetitions, duration of repetitions, the order of exercises, number of series, recovery intervalbetween series, and the exercises, as well as the time under tension. The influence of the recovery interval on the responsefollowing exercise on neuromuscular components is very important. However, different objectives, and instruments are usedto evaluate these responses.Objective: The purpose of this study is to conduct a systematic review of the assessment methods, and objectives for respon-ses after different recovery intervals in strength training. METHODS: The present study is characterized by a systematic reviewstudy. Articles found in the following databases were considered for the systematic review: Scopus, PubMed / MEDLINE, Webof Science, Cochrane Library. The following descriptors, and their respective synonyms according to the terms MeSH wereused in the databases, both singular, and plural: Resistance Training, Rest Interval, and Bech Press. As filters were used: a)species (humans), and type of study (original).Results: Seven studies were analyzed that met the established criteria.Conclusion: The studies presented have verified the influence of different recovery intervals on muscle, and hemodynamicresponses. Evaluating image measurements such as ultrasound, and resonance, blood measurements such as GH, Testosterone,IGF-1, and Lactate, number of repetitions for performance, and fatigue, as well as heart rate, and blood pressure.(AU)
Introducción: La rutina de entrenamiento planificada y realizada correctamente da como resultado ejercicios que, organizadossistemáticamente, influyen en los niveles de fuerza e hipertrofia muscular. Sin embargo, las magnitudes de estas gananciasvarían considerablemente. Para optimizar estas ganancias, es importante comprender la interacción entre las variables deentrenamiento como la carga externa, el volumen, el número de ejercicios, el número de repeticiones, la duración de lasrepeticiones, el orden de los ejercicios, el número de series, el intervalo de recuperación entre series y los ejercicios, así comoel tiempo bajo tensión. La influencia del intervalo de recuperación en la respuesta después del ejercicio en los componentesneuromusculares es muy importante. Sin embargo, se utilizan diferentes objetivos e instrumentos para evaluar estas respuestas.Objetivo: El propósito de este estudio es realizar una revisión sistemática de los métodos y objetivos de evaluación paralas respuestas posteriores a los diferentes intervalos de recuperación en el entrenamiento de fuerza. MÉTODOS: El presenteestudio se caracteriza por un estudio de revisión sistemática. Los artículos encontrados en las siguientes bases de datos seconsideraron para la revisión sistemática: Scopus, PubMed / MEDLINE, Web of Science, Cochrane Library. Los siguientes des-criptores y sus respectivos sinónimos según los términos MeSH se utilizaron en las bases de datos, tanto en singular como enplural: Entrenamiento de resistencia, Intervalo de descanso y Bench Press. Como filtros se utilizaron: a) especies (humanos)y tipo de estudio (original).Resultados: Se analizaron siete estudios que cumplieron con los criterios establecidos.Conclusión: Los estudios presentados han verificado la influencia de diferentes intervalos de recuperación en las respuestasmusculares y hemodinámicas. Evaluación de mediciones de imagen como ultrasonido y resonancia...(AU)
