[Detection and localization of multiple metastases from differentiated thyroid carcinoma with 99mTc-MIBI whole body scintigraphy: a case report].

A 79-year-old male with a history of total thyroidectomy due to follicular thyroid carcinoma developed multiple metastases in the lung, bone, and lymph nodes. In order to detect and localize every metastases, 99mTc-MIBI whole body scintigraphy was performed, and clearly depicted all metastatic lesions except tiny pulmonary nodules. 99mTc-MIBI whole body scintigraphy may be useful in detecting metastases from differentiated thyroid carcinoma, because of a good quality of scintigram and no need of patient preparation. This article is the first report on 99mTc-MIBI localization in multiple metastases from differentiated thyroid carcinoma.

A case of liver echinococcosis mimicing a solid liver tumor.

A case of hepatic echinococcosis mimicing a solid tumor was presented. The echinococcosis appeared as an echogenic mass in US, a low density area in CT, and an area of low (T1-weighted image) and high (T2-weighted image) intensity in MRI. Echo-guided biopsy showed PAS-positive cuticle layer of echinococcus in the necrotic tissue. Anular features around the lesion noted in MRI seemed to imply increased hepatic tissue water (congestion and/or edema). When a solid tumor is noted in the liver, proper history taking and awareness of this disease will decrease the chance of misdiagnosis.

[Post-treatment changes of skeletal Class III morphology operated by orthognathic two-jaw surgery].

The purpose of this study was to investigate the dentofacial changes following orthognathic Two-jaw surgery in skeletal Class III patients. The materials consisted of cephalometric head films of 20 patients who had simultaneously undergone Le Fort I osteotomy and mandibular ramus osteotomy. All cases received the pre- and post-operative orthodontic treatment and had the observation periods over than one year after postoperative orthodontic treatment. The cephalometric radiographs were taken at following five stages: 1. Before preoperative orthodontic treatment, 2. Immediately before surgery, 3. After intermaxillary fixation, 4. After postoperative orthodontic treatment, and 5. Posttreatment observation period. The results were as follows: 1. The anteroposterior skeletal relapse was minimum after surgery. 2. The surgical manner of the maxillary vertical displacement did not effect the stability of the upper facial height after surgery. The lower facial height tended to decrease slightly during postoperative orthodontic treatment. 3. The upper and lower incisors showed lingual tipping during intermaxillary fixation, but the upper incisors tipped labially during retention period. In conclusions, Two-jaw surgery was considered to be quite effective for the correction of skeletal Class III malocclusions especially with the maxillary deficiency.

In vivo localization of radiolabeled monoclonal antibody to carcinoembryonic antigen (CEA) in a CEA-producing tumor--comparison with polyclonal antibody.

To compare accumulation of the 125I-labeled antibodies (anti-carcinoembryonic antigen (CEA) monoclonal antibody and polyclonal antibody) to a CEA-producing tumor (SC-2-JCK), an in vivo localization study was performed in nude mice. The tumor-to-blood ratio at 120 hours after injection rose to 4.6 for the monoclonal antibody, but remained at 1.3 for the polyclonal antibody. However, no differences were noted between the antibodies up to 72 hours after injection. In autoradiograms, selective accumulation of the tracer was noted in the tumor for both antibodies. However, no superiority or inferiority of imaging for either of the antibodies could be definitely determined.

Evaluation of the degree of severity in liver cirrhosis by computed tomography.

As CT findings useful for the evaluation of the degree of severity in liver cirrhosis, the following items were chosen for statistical analysis: atrophy of the right lobe, enlargement of the left lobe, irregularity of the liver surface, ascites, varices or collaterals, and dilatation of the SMV. According to the frequency with which these six items were found, the CT findings were expressed in the form of a score, and the resulting scores agreed well with ICG values, portal-venous flow (Qp) ratios obtained from radionuclide angiography, and the scores on the Child-Turcotte criteria. A score of 5 or 6 meant severe cirrhosis. A score of 4 meant liver cirrhosis, however, the degree of severity could not be determined, because there was overlap among the cirrhotic groups. A score of 3 meant liver cirrhosis with a probability of about 90%. A score of 1 or 2 was nonspecific for evaluation. When a score of 0 was noted with splenomegaly, there was a probability of more than 90% that it was chronic hepatitis. In conclusion, this approach was considered to be useful for evaluating the degree of severity in liver cirrhosis and differentiating between liver cirrhosis and chronic hepatitis to some degree in Japanese.