Point-of-care ultrasound (POCUS) in acute hospitalized older patients focused on hydration.

BACKGROUND: Acutely ill older patients frequently suffer not only from their acute disease, but also polymorbidity and frailty. Dehydration is another typical symptom, usually occurring in its both forms: low-intake dehydration and volume depletion. POCUS is goal-directed bedside ultrasound examination and several studies refer to its positive impact on hydration assessment. The aim of our study was to determine whether POCUS might influence (de)hydration diagnostics and/or treatments in older patients with acute illness. METHODS: We randomized 120 acutely ill patients, aged ≥65 years, into POCUS and non-POCUS groups. All participants underwent routine laboratory tests, including haematocrit, serum and urine osmolality, blood urea nitrogen (BUN), creatinine, BUN/creatinine ratio, and C-reactive protein (CRP). POCUS was performed twice during the first two days to determine chest and abdominal status, with inferior vena cava (IVC) measurements. Length of hospital stay (HL) and consumption of infused fluids (CIF) was evaluated too. Data were analysed with exploratory methods and appropriate statistics. RESULTS: Among all participants, the serum osmolality significantly correlated with age, BUN, creatinine and CIF. HL correlated with CRP and CIF. No significant correlations between IVC and other followed parameters were found. The POCUS group consumed significantly less infused fluids than the non-POCUS group, what could be influenced by POCUS examination of defined body compartments. CONCLUSION: Dehydration is a common feature in older individuals and its diagnostics is rather complicated. The role of POCUS in assessing hydration status remains unclear. However, our study showed, that ultrasound assessment provides next important information for comprehensive understanding of clinical status in older patients and can be beneficial for optimizing the treatment strategy, including fluid management decisions.

Student and faculty perceptions of nutrition education in medical school.

BACKGROUND & AIM: There is abundant evidence to support the beneficial role of nutrition in the prevention, management and treatment of many health conditions including non-communicable diseases and malnutrition. Despite the increasing prevalence of these conditions around the world, research over the past decades has identified that many medical schools lack adequate nutrition education and training for medical students. With the Czech Republic not represented in these findings, this qualitative study aimed to assess and describe the perceptions of nutrition education at a Czech medical school. METHODS: Thirty-six participants, including students in all grades (n = 30) and faculty members from different disciplines (n = 6), completed individual, semi-structured interviews. Interviews were audio-recorded and transcribed verbatim. Inductive coding and thematic analysis were used to analyze data and identify key themes. RESULTS: Participants emphasized the important and wide-ranging role of nutrition, describing it as significant and essential for both prevention and treatment of many medical conditions. The first main theme, 'Nutrition in Medical Care and Health' identified support for the important role that nutrition plays in medical care and health. Participants acknowledged that doctors have an important role to promote good nutrition and thus require sufficient education in medical school to offer general nutrition information to patients. In the second theme, 'Nutrition Education in the Current Curriculum' some participants acknowledged that while the medical school offers a good theoretical education about nutrition, and training for specific populations such as pediatrics and oncology, overall, the current education about nutrition was 'inadequate,' not emphasized like other subjects and lacked practical application in clinical practice. The third main theme 'Opportunities for Nutrition Education in Medical School' identified the students' interest in learning more about nutrition to improve their knowledge in preparation for future practice and to promote healthy eating during medical school. In addition to identifying specific topics of interest, the participants shared preferred methods of learning nutrition information. CONCLUSIONS: The participants in this study recognized the importance of nutrition in medical care and perceived that nutrition education is not emphasized consistently in medical school. Students desired additional nutrition education to include current topics, promote self-care, and improve the emphasis in clinical training.

Osteolytic bone lesions, hypercalcemia and paraprotein, but not a myeloma: case report and review of literature.

In June 2018, 77-year-old man was referred to The Department of Haematooncology, University Hospital Ostrava, for suspicion of multiple myeloma. This was supported by laboratory findings of hypercalcemia, paraprotein IgA κ in serum and by the presence of multiple osteolytic skeletal lesions. Low number of plasma cells in bone marrow sample - cytologically (3.6 %) as well as in flow cytometry (less than 95 % clonal plasma cells out of total bone marrow plasma cells) - pointed at the direction of monoclonal gammopathy of undetermined significance (MGUS). In the course of differential diagnosis of hypercalcemia, elevated level of parathormone had been found which led to the performance of 99mTc-MIBI scintigraphy where parathyroid adenoma was discovered and later histologically verified. The final diagnosis was determined as a coincidence of MGUS and primary hyperparathyroidism. This case report also contains brief differential diagnosis of hypercalcemia and osteolytic skeletal lesions and suggestions for their diagnostic algorithms.