1.
Chemistry
; 21(49): 17596-600, 2015 Dec 01.
Article
in English
| MEDLINE
| ID: mdl-26463116
ABSTRACT
A conceptually new light-up nucleic acid fluorescent probe resulting from the conjugation of a coumarin to a naphthalene diimide exhibits a single wavelength emission at 498â nm when free in solution and an additional red/NIR emission when bound to G-quadruplex DNA. The light-up response centred at 666â nm is highly specific for quadruplex DNA when compared to duplex DNA or to RNA quadruplexes.