1.
J Agric Food Chem
; 47(1): 318-21, 1999 Jan.
Article
in English
| MEDLINE
| ID: mdl-10563892
ABSTRACT
The phosphosulfonates are a new class of soil-active herbicides which control a variety of annual grass and broadleaf weeds. Chirality at the phosphorus atom afforded the opportunity to explore stereospecific requirements for herbicidal activity. Chiral (hydroxymethyl)phosphinate intermediates were enzymatically resolved (Pseudomonas fluorescens lipase) from the racemic mixtures and then used to prepare two pairs of enantiomeric phosphosulfonates. Biological testing of the enantiomeric phosphosulfonate herbicides demonstrated that, in each case, the herbicidal activity was attributed to the (+) enantiomer and that the (+) enantiomer is more active than the racemate.
Subject(s)
Herbicides , Sulfonic Acids , Herbicides/chemical synthesis , Organophosphorus Compounds/chemistry , Stereoisomerism , Sulfonic Acids/chemical synthesis , Sulfonic Acids/chemistry
2.
Tex Med
; 94(7): 49-51, 1998 Jul.
Article
in English
| MEDLINE
| ID: mdl-9664819