ABSTRACT
The case of a 64-year-old white man with acquired immunodeficiency syndrome and ruptured abdominal aortic aneurysm infected with Salmonella is presented. Five points related to this case are addressed. It is feared that the vascular surgeon may face patients with acquired immunodeficiency syndrome and abdominal aortic aneurysms infected with Salmonella with increasing frequency in the future. This case raises medical, ethical, and moral questions.
Subject(s)
Acquired Immunodeficiency Syndrome/complications , Aortic Aneurysm/complications , Acquired Immunodeficiency Syndrome/surgery , Aorta, Abdominal , Aortic Aneurysm/surgery , Humans , Male , Middle Aged , Salmonella Infections/complicationsABSTRACT
A cytomorphological description of lobular carcinoma of the breast is given based on imprints, paraffin-embedded 5-mu sections, and plastic-embedded 2-mu sections in nine patients. Both nuclear and cytoplasmic features are illustrated and tabulated. A basic lobular carcinoma cell is depicted. Cytoplasmic vacuolization is demonstrated in all tumors. Transitions from one lobular cell variation to another are demonstrated. It is suggested that more precise knowledge of the similarities and the variations in the morphology of the lobular carcinoma cell will help in both cytological and histological diagnosis.
Subject(s)
Breast Neoplasms/pathology , Breast Neoplasms/diagnosis , Cell Nucleus/pathology , Cytodiagnosis , Cytoplasm/pathology , False Negative Reactions , Female , Humans , Vacuoles/pathologyABSTRACT
Although chrondrosarcomas are common primary bone tumors, their occurrence in the spine is very rare. Because total excision in such cases is seldom possible, few long term survivors have been reported. We are reporting one patient with a high thoracic spinal chondrosarcoma who survived with useful function for over 18 years because of repeated local tumor excisions. The literature is reviewed, and an aggressive surgical treatment of spinal chondrosarcoma is recommended.
Subject(s)
Chondrosarcoma/surgery , Spinal Neoplasms/surgery , Thoracic Vertebrae/surgery , Female , Follow-Up Studies , Humans , Laminectomy , Middle Aged , Neoplasm Recurrence, Local/surgery , Reoperation , Spinal Cord Compression/surgeryABSTRACT
Metastatic spinal cancer is common and usually involves the bony spine or the epidural space. We are reporting a case of breast carcinoma metastatic to the spinal subdural space, and we review the literature concerning this unusual metastatic site. Unlikely metastatic locations should be suspected whenever myelography in cancer patients with spinal cord signs is confusing.
Subject(s)
Adenocarcinoma/secondary , Breast Neoplasms/surgery , Spinal Cord Neoplasms/secondary , Adenocarcinoma/surgery , Adult , Female , Humans , Laminectomy , Myelography , Nerve Compression Syndromes/surgery , Spinal Cord Compression/surgery , Spinal Cord Neoplasms/surgery , Spinal Nerve Roots/surgery , Subdural SpaceABSTRACT
Intracerebral hematomas producing chronic neurological disability are reported rarely. Two cases of chronic intracerebral hematoma are described. Each case was associated with a thick, fibrous capsule found histologically to arise from an occult vascular malformation. When such encapsulation is discovered surgically, a vascular anomaly must be suspected.
Subject(s)
Cerebral Hemorrhage/diagnosis , Hematoma/diagnosis , Aged , Cerebral Hemorrhage/diagnostic imaging , Cerebral Hemorrhage/pathology , Chronic Disease , Hematoma/diagnostic imaging , Hematoma/pathology , Humans , Male , Middle Aged , Tomography, X-Ray ComputedABSTRACT
Pseudomembranous colitis has been observed increasingly often after therapy with several antibiotics. This report describes the case of a patient in whom pseudomembranous colitis developed in association with ampicillin, an extremely rare complication of this drug, and erythromycin, a drug that has not been previously reported to cause the disease. Clinical and pathologic features, pathogenesis, and management are discussed. Early diagnosis and treatment are extremely important to reduce the significant morbidity and mortality associated with this disorder.
Subject(s)
Ampicillin/adverse effects , Enterocolitis, Pseudomembranous/chemically induced , Erythromycin/adverse effects , Aged , Colon/pathology , Enterocolitis, Pseudomembranous/diagnosis , Enterocolitis, Pseudomembranous/drug therapy , Enterocolitis, Pseudomembranous/pathology , Female , Humans , RecurrenceABSTRACT
This report, based on eight cases of our own and a review of the literature, indicates that colonic cancer metastatic to the ovaries has many unusual features and an extremley high mortality rate. Prophylactic bilateral oophorectomy in conjunction with large-bowel resection for cancer in women of all ages is strongly advised to decrease morbidity and improve the quality of survival.
Subject(s)
Adenocarcinoma/surgery , Castration , Intestinal Neoplasms/surgery , Intestine, Large/surgery , Ovarian Neoplasms/prevention & control , Cecal Neoplasms/surgery , Colonic Neoplasms/surgery , Female , Humans , Middle Aged , Neoplasm MetastasisABSTRACT
A patient who abused multiple drugs developed a rapidly progressive mononeuropathy multiplex, which appeared to respond to corticosteroid therapy with partial resolution. Intravenous methamphetamine had been used almost exclusively from the fourth month prior to the onset of symptoms. Biopsy material revealed a necrotizing angiitis involving medium and small sized arteries, capillaries, and venules, typical of a hypersensitivity-type angiopathy, rather than the previously reported polyarteritis nodosa-type lesions secondary to illicit drugs. The apparent response to corticosteroids suggests that these agents might be useful in the treatment of some complications of drug abuse.
