Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Database
Language
Publication year range
1.
Therapie ; 76(2): 75-86, 2021.
Article in English | MEDLINE | ID: mdl-33358639

ABSTRACT

The multiple brain circuits involved in psychiatric diseases may appear daunting, but we prefer to concentrate on a select few, with a particular sensitivity to stress and neurodevelopmental issues, with a clear pharmacotherapy. This review is structured around 1. the key circuits, their role in health and disease, and the neurotransmitters maintaining them, 2. The influence of upbringing, stress, chronobiology, inflammation and infection, 3. The genetic and epigenetic influence on these circuits, particularly regarding copy number variants and neuronal plasticity, 4. The use and abuse of pharmacological agents with the particular risks of stress and chronobiology at critical periods. A major emphasis is placed on the links between hippocampus, prefrontal cortex and amygdala/periaqueductal grey which control specific aspects of cognition, mood, pain and even violence. Some of the research findings were from the innovative medicine initiative (IMI) NEWMEDS, a 22M€ academic/industrial consortium on the brain circuits critical for psychiatric disease.


Subject(s)
Mental Disorders , Amygdala , Hippocampus , Humans , Prefrontal Cortex
2.
Dent Update ; 29(2): 59-62, 2002 Mar.
Article in English | MEDLINE | ID: mdl-11928341

ABSTRACT

Gingival recession affects a large proportion of the adult population. This paper discusses the aetiology and mechanisms behind the formation of gingival recession, and considers the relevance of gingival recession to both orthodontics and restorative dentistry. It is followed by a second paper on the management of gingival recession.


Subject(s)
Gingival Recession/etiology , Adult , Aged , Chronic Disease , Dental Plaque/complications , Dental Restoration, Permanent/adverse effects , Gingiva/pathology , Gingivitis/complications , Humans , Labial Frenum/pathology , Middle Aged , Orthodontic Appliances , Surface Properties , Tooth Eruption , Tooth Movement Techniques , Toothbrushing/adverse effects
SELECTION OF CITATIONS
SEARCH DETAIL
...