ABSTRACT
The most methods for induction of an experimental arterial thrombosis needs an operative procedure. A method for non-operative induction of thrombosis in peripheric big arteries is presented in this contribution. The technique is endovasal and transcatheteral. The contact of the endovasal electrode with the arterial intima has to be guaranteed for a certain thrombosis. A particularly constructed electrode for application of direct current in big arteries is presented to the realization of this demand.
Subject(s)
Carotid Artery Thrombosis/etiology , Electric Stimulation/methods , Femoral Artery/diagnostic imaging , Thrombosis/etiology , Animals , Carotid Artery Thrombosis/diagnostic imaging , Disease Models, Animal , Dogs , Electric Stimulation/instrumentation , Radiography , Thrombosis/diagnostic imagingABSTRACT
Coronary thrombosis is a perilous disease. Animal experiments may contribute to investigate its pathogenesis and treatment. The development of an experimental model of coronary thrombosis on closed thorax is important. In this report the methodics of such model is entered into, pointing at its dangers and possible complications.