Evidence-Based Medicine and Pharmacotherapy Content Alignment.

OBJECTIVE: When effectively executed, content alignment can aid student performance in associated courses. Limited research exists for content alignment of evidence-based medicine (EBM) and pharmacotherapy courses. This study assesses the impact of EBM and pharmacotherapy course alignment on student performance. METHODS: Content alignment included assignment of 6 landmark trials in EBM coursework. The articles were identified by pharmacotherapy instructors as "landmark" to management of associated diseases in the aligned pharmacotherapy semester. Articles were the basis for quizzes over skills taught in the EBM course and were referenced during pharmacotherapy lectures. RESULTS: During the alignment semester, students were more likely to cite specific guidelines and/or primary literature to rationalize pharmacotherapeutic plans on examinations compared with the prealignment period (54% vs 34%). Overall, pharmacotherapy case performance and plan rationale scores were significantly higher in the alignment semester compared with prealignment. Student performance on the Assessing Competency in Evidence-Based Medicine tool improved from the start of the semester (8.64, SD 1.66) to the end (9.5, SD 1.49; mean score +0.86). Comfort in applying EBM analysis to primary literature increased significantly between the first and final assignments, with 6.7% and 71.7% of students self-reporting a high degree of confidence, respectively. Students (73%) reported an enhanced understanding of pharmacotherapy due to alignment compared with a previous semester of pharmacotherapy without alignment. CONCLUSION: The use of landmark trial assignments to align EBM and pharmacotherapy coursework demonstrated a positive impact on student rationale for clinical decision-making and student confidence in evaluating primary literature.

Impact of COVID-19 health information sources on student vaccine hesitancy.

BACKGROUND: The purpose of this study was to determine how health care professional and undergraduate students stay informed on COVID-19 and which characteristics influence the decision to receive or recommend a vaccine to focus efforts on addressing misinformation and vaccine hesitancy. METHODS: A 13-item survey was administered to currently enrolled undergraduate and health care students (including nursing, dental, medical, and pharmacy) within the same university. Students were asked to rate their utilization and trust of COVID-19 resources and were asked about the importance and challenges of staying current with COVID-19 information. Student willingness to receive the vaccine was also assessed. RESULTS: The school of pharmacy had the highest percentage of students (88.3%, n = 159) who would receive the vaccine. Only 73.6% (n = 323) of undergraduate students reported they would be willing. Students who were willing to receive the vaccine had higher average scores of trust for scientific journals, school curriculum/coursework, and school communication and utilized these sources for COVID-19 information more than those who would not receive the vaccine and were unsure about receiving the vaccine. CONCLUSIONS: This study confirms that students who were most trusting of their COVID-19 information sources were more likely to receive the vaccine. Pharmacy students relied heavily on information provided by the school curriculum/coursework, indicating the need for pharmacy faculty to include methods of addressing vaccine hesitancy such as simulation modules and the Pharmacists' Patient Care Process to help students combat vaccine hesitancy and misinformation when communicating with patients.

Accuracy of Medical Marijuana Claims Made by Popular Websites.

BACKGROUND: With increasing popularity of marijuana, consumers are likely turning to the internet for information regarding medical marijuana. Accuracy of medical marijuana claims is a significant concern because consumers change their medication management based on information from a single website. OBJECTIVE: The purpose of this study was to evaluate the accuracy and quality of medical marijuana claims on popular websites. Methods : Commonly used websites containing claims regarding medical marijuana were selected by utilizing three online marketing tools that rank websites based on number of views, number of visitors, and visitor engagement. Once the top ten most popular websites were selected, medical claims regarding marijuana were reviewed for accuracy and quality using evidence-based tools. RESULTS: Seventy-six percent of claims made by websites were inaccurate and were based on low-quality evidence. Of the medical marijuana claims reviewed, 10% of websites made appropriate cause and effect conclusions. Furthermore, approximately 3% of the medical marijuana claims were written by a healthcare professional. CONCLUSION: The findings show there is misleading and inaccurate information readily available to consumers online.

Dietary supplements for osteoarthritis.

A large number of dietary supplements are promoted to patients with osteoarthritis and as many as one third of those patients have used a supplement to treat their condition. Glucosamine-containing supplements are among the most commonly used products for osteoarthritis. Although the evidence is not entirely consistent, most research suggests that glucosamine sulfate can improve symptoms of pain related to osteoarthritis, as well as slow disease progression in patients with osteoarthritis of the knee. Chondroitin sulfate also appears to reduce osteoarthritis symptoms and is often combined with glucosamine, but there is no reliable evidence that the combination is more effective than either agent alone. S-adenosylmethionine may reduce pain but high costs and product quality issues limit its use. Several other supplements are promoted for treating osteoarthritis, such as methylsulfonylmethane, Harpagophytum procumbens (devil's claw), Curcuma longa (turmeric), and Zingiber officinale (ginger), but there is insufficient reliable evidence regarding long-term safety or effectiveness.