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Eksp Klin Gastroenterol ; (10): 77-82, 2014.
Article in Russian | MEDLINE | ID: mdl-25911936

ABSTRACT

A review of the literature, the authors present information about angiogenesis, as the process of formation of new blood vessels in the organ or tissue from pre-existing vasculature by migration and proliferation of endothelial cells, as well as on the processes of regulation. Presents key regulatory system angiogenesis. The main attention is paid Vascular endothelial growth factor (VEGF). Specially structured data on the role of Vascular endothelial growth factor in human pathology, including diseases of gastrointestinal tract, inflammatory and neoplastic nature.


Subject(s)
Gastrointestinal Neoplasms/blood supply , Gastrointestinal Tract/blood supply , Neovascularization, Pathologic/pathology , Vascular Endothelial Growth Factor A/metabolism , Endothelium, Vascular/metabolism , Endothelium, Vascular/pathology , Endothelium, Vascular/physiopathology , Gastrointestinal Neoplasms/metabolism , Gastrointestinal Neoplasms/physiopathology , Gastrointestinal Tract/metabolism , Humans , Microcirculation/physiology , Neovascularization, Pathologic/metabolism , Neovascularization, Pathologic/physiopathology , Neovascularization, Physiologic/drug effects , Neovascularization, Physiologic/physiology
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