ABSTRACT
Marked differences in CSF levels of both calcium and phosphorus were observed in patients with dementia and aged controls when compared with adult controls. A significant decrease in both Ca and P in CSF was observed in Alzheimer's type dementia (p less than 0.01) and multi-infarct dementia cases (p less than 0.01). The geriatric controls also showed a significant decrease in both Ca and P. A 60% decrease in diffusible Ca in CSF was noted both in patients and geriatric controls when compared to adult controls (p less than 0.001). Diffusible P was also decreased in all three groups (p less than 0.05). A marginal decrease in serum Ca and slight increase in P was observed in both patients and geriatric controls. The significant decrease in CSF Ca and P in both groups of patients compared with aged controls suggests this lowering of Ca and P is not due to solely to the aging process and indicates a role in the pathology of age-related disorders.
Subject(s)
Calcium/blood , Calcium/cerebrospinal fluid , Dementia/blood , Dementia/cerebrospinal fluid , Phosphorus/blood , Phosphorus/cerebrospinal fluid , Adult , Aged , Alzheimer Disease/blood , Alzheimer Disease/cerebrospinal fluid , Alzheimer Disease/psychology , Dementia/psychology , Dementia, Multi-Infarct/blood , Dementia, Multi-Infarct/cerebrospinal fluid , Dementia, Multi-Infarct/psychology , Female , Humans , India , Male , Middle Aged , Psychiatric Status Rating ScalesSubject(s)
Alzheimer Disease/cerebrospinal fluid , Zinc/cerebrospinal fluid , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Sex FactorsSubject(s)
Bipolar Disorder/complications , Retinal Hemorrhage/psychology , Vitreous Hemorrhage/psychology , Adult , Humans , MaleABSTRACT
Comparison of C.S. F. H. V. A and 5-HIAA levels of 20 Schizophrenics and 9 non-schizophrenic controls revealed no statistically significant difference between HVA levels but the 5-HIAA levels were significantly less in Schizophrenics (p < 0.05) than in controls. The significance of these findings is discussed.
ABSTRACT
A rare case report of association of affective psychosis with pyknodysostosis is discussed.
