An explainable Artificial Intelligence software system for predicting diabetes.

Implementing diabetes surveillance systems is paramount to mitigate the risk of incurring substantial medical expenses. Currently, blood glucose is measured by minimally invasive methods, which involve extracting a small blood sample and transmitting it to a blood glucose meter. This method is deemed discomforting for individuals who are undergoing it. The present study introduces an Explainable Artificial Intelligence (XAI) system, which aims to create an intelligible machine capable of explaining expected outcomes and decision models. To this end, we analyze abnormal glucose levels by utilizing Bi-directional Long Short-Term Memory (Bi-LSTM) and Convolutional Neural Network (CNN). In this regard, the glucose levels are acquired through the glucose oxidase (GOD) strips placed over the human body. Later, the signal data is converted to the spectrogram images, classified as low glucose, average glucose, and abnormal glucose levels. The labeled spectrogram images are then used to train the individualized monitoring model. The proposed XAI model to track real-time glucose levels uses the XAI-driven architecture in its feature processing. The model's effectiveness is evaluated by analyzing the performance of the proposed model and several evolutionary metrics used in the confusion matrix. The data revealed in the study demonstrate that the proposed model effectively identifies individuals with elevated glucose levels.

An Interpretable Approach with Explainable AI for Heart Stroke Prediction.

Heart strokes are a significant global health concern, profoundly affecting the wellbeing of the population. Many research endeavors have focused on developing predictive models for heart strokes using ML and DL techniques. Nevertheless, prior studies have often failed to bridge the gap between complex ML models and their interpretability in clinical contexts, leaving healthcare professionals hesitant to embrace them for critical decision-making. This research introduces a meticulously designed, effective, and easily interpretable approach for heart stroke prediction, empowered by explainable AI techniques. Our contributions include a meticulously designed model, incorporating pivotal techniques such as resampling, data leakage prevention, feature selection, and emphasizing the model's comprehensibility for healthcare practitioners. This multifaceted approach holds the potential to significantly impact the field of healthcare by offering a reliable and understandable tool for heart stroke prediction. In our research, we harnessed the potential of the Stroke Prediction Dataset, a valuable resource containing 11 distinct attributes. Applying these techniques, including model interpretability measures such as permutation importance and explainability methods like LIME, has achieved impressive results. While permutation importance provides insights into feature importance globally, LIME complements this by offering local and instance-specific explanations. Together, they contribute to a comprehensive understanding of the Artificial Neural Network (ANN) model. The combination of these techniques not only aids in understanding the features that drive overall model performance but also helps in interpreting and validating individual predictions. The ANN model has achieved an outstanding accuracy rate of 95%.

Using Recurrent Neural Networks for Predicting Type-2 Diabetes from Genomic and Tabular Data.

The development of genomic technology for smart diagnosis and therapies for various diseases has lately been the most demanding area for computer-aided diagnostic and treatment research. Exponential breakthroughs in artificial intelligence and machine intelligence technologies could pave the way for identifying challenges afflicting the healthcare industry. Genomics is paving the way for predicting future illnesses, including cancer, Alzheimer's disease, and diabetes. Machine learning advancements have expedited the pace of biomedical informatics research and inspired new branches of computational biology. Furthermore, knowing gene relationships has resulted in developing more accurate models that can effectively detect patterns in vast volumes of data, making classification models important in various domains. Recurrent Neural Network models have a memory that allows them to quickly remember knowledge from previous cycles and process genetic data. The present work focuses on type 2 diabetes prediction using gene sequences derived from genomic DNA fragments through automated feature selection and feature extraction procedures for matching gene patterns with training data. The suggested model was tested using tabular data to predict type 2 diabetes based on several parameters. The performance of neural networks incorporating Recurrent Neural Network (RNN) components, Long Short-Term Memory (LSTM), and Gated Recurrent Units (GRU) was tested in this research. The model's efficiency is assessed using the evaluation metrics such as Sensitivity, Specificity, Accuracy, F1-Score, and Mathews Correlation Coefficient (MCC). The suggested technique predicted future illnesses with fair Accuracy. Furthermore, our research showed that the suggested model could be used in real-world scenarios and that input risk variables from an end-user Android application could be kept and evaluated on a secure remote server.

ResNet-32 and FastAI for diagnoses of ductal carcinoma from 2D tissue slides.

Carcinoma is a primary source of morbidity in women globally, with metastatic disease accounting for most deaths. Its early discovery and diagnosis may significantly increase the odds of survival. Breast cancer imaging is critical for early identification, clinical staging, management choices, and treatment planning. In the current study, the FastAI technology is used with the ResNet-32 model to precisely identify ductal carcinoma. ResNet-32 is having few layers comparted to majority of its counterparts with almost identical performance. FastAI offers a rapid approximation toward the outcome for deep learning models via GPU acceleration and a faster callback mechanism, which would result in faster execution of the model with lesser code and yield better precision in classifying the tissue slides. Residual Network (ResNet) is proven to handle the vanishing gradient and effective feature learning better. Integration of two computationally efficient technologies has yielded a precision accuracy with reasonable computational efforts. The proposed model has shown considerable efficiency in the evaluating parameters like sensitivity, specificity, accuracy, and F1 Score against the other dominantly used deep learning models. These insights have shown that the proposed approach might assist practitioners in analyzing Breast Cancer (BC) cases appropriately, perhaps saving future complications and death. Clinical and pathological analysis and predictive accuracy have been improved with digital image processing.

AAL and Internet of Medical Things for Monitoring Type-2 Diabetic Patients.

Due to an aging population, assisted-care options are required so that senior citizens may maintain their independence at home for a longer time and rely less on caretakers. Ambient Assisted Living (AAL) encourages the creation of solutions that can help to optimize the environment for senior citizens with assistance while greatly reducing their challenges. A framework based on the Internet of Medical Things (IoMT) is used in the current study for the implementation of AAL technology to help patients with Type-2 diabetes. A glucose oxide sensor is used to monitor diabetic elderly people continuously. Spectrogram images are created from the recorded data from the sensor to assess and detect aberrant glucose levels. DenseNet-169 examines and analyzes the spectrogram pictures, and messages are sent to caregivers when aberrant glucose levels are detected. The current work describes both the spectrogram image analysis and the signal-to-spectrogram generating method. The study presents a future perspective model for a mobile application for real-time patient monitoring. Benchmark metrics evaluate the application's performances, including sensitivity, specificity, accuracy, and F1-score. Several cross--validations are used to evaluate the model's performance. The findings demonstrate that the proposed model can correctly identify patients with abnormal blood glucose levels.

Fine-Tuned DenseNet-169 for Breast Cancer Metastasis Prediction Using FastAI and 1-Cycle Policy.

Lymph node metastasis in breast cancer may be accurately predicted using a DenseNet-169 model. However, the current system for identifying metastases in a lymph node is manual and tedious. A pathologist well-versed with the process of detection and characterization of lymph nodes goes through hours investigating histological slides. Furthermore, because of the massive size of most whole-slide images (WSI), it is wise to divide a slide into batches of small image patches and apply methods independently on each patch. The present work introduces a novel method for the automated diagnosis and detection of metastases from whole slide images using the Fast AI framework and the 1-cycle policy. Additionally, it compares this new approach to previous methods. The proposed model has surpassed other state-of-art methods with more than 97.4% accuracy. In addition, a mobile application is developed for prompt and quick response. It collects user information and models to diagnose metastases present in the early stages of cancer. These results indicate that the suggested model may assist general practitioners in accurately analyzing breast cancer situations, hence preventing future complications and mortality. With digital image processing, histopathologic interpretation and diagnostic accuracy have improved considerably.

Empirical Study on Classifiers for Earlier Prediction of COVID-19 Infection Cure and Death Rate in the Indian States.

Machine Learning methods can play a key role in predicting the spread of respiratory infection with the help of predictive analytics. Machine Learning techniques help mine data to better estimate and predict the COVID-19 infection status. A Fine-tuned Ensemble Classification approach for predicting the death and cure rates of patients from infection using Machine Learning techniques has been proposed for different states of India. The proposed classification model is applied to the recent COVID-19 dataset for India, and a performance evaluation of various state-of-the-art classifiers to the proposed model is performed. The classifiers forecasted the patients' infection status in different regions to better plan resources and response care systems. The appropriate classification of the output class based on the extracted input features is essential to achieve accurate results of classifiers. The experimental outcome exhibits that the proposed Hybrid Model reached a maximum F1-score of 94% compared to Ensembles and other classifiers like Support Vector Machine, Decision Trees, and Gaussian Naïve Bayes on a dataset of 5004 instances through 10-fold cross-validation for predicting the right class. The feasibility of automated prediction for COVID-19 infection cure and death rates in the Indian states was demonstrated.

Classification of Skin Disease Using Deep Learning Neural Networks with MobileNet V2 and LSTM.

Deep learning models are efficient in learning the features that assist in understanding complex patterns precisely. This study proposed a computerized process of classifying skin disease through deep learning based MobileNet V2 and Long Short Term Memory (LSTM). The MobileNet V2 model proved to be efficient with a better accuracy that can work on lightweight computational devices. The proposed model is efficient in maintaining stateful information for precise predictions. A grey-level co-occurrence matrix is used for assessing the progress of diseased growth. The performance has been compared against other state-of-the-art models such as Fine-Tuned Neural Networks (FTNN), Convolutional Neural Network (CNN), Very Deep Convolutional Networks for Large-Scale Image Recognition developed by Visual Geometry Group (VGG), and convolutional neural network architecture that expanded with few changes. The HAM10000 dataset is used and the proposed method has outperformed other methods with more than 85% accuracy. Its robustness in recognizing the affected region much faster with almost 2× lesser computations than the conventional MobileNet model results in minimal computational efforts. Furthermore, a mobile application is designed for instant and proper action. It helps the patient and dermatologists identify the type of disease from the affected region's image at the initial stage of the skin disease. These findings suggest that the proposed system can help general practitioners efficiently and effectively diagnose skin conditions, thereby reducing further complications and morbidity.