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Experientia ; 52(1): 5-13, 1996 Jan 16.
Article in English | MEDLINE | ID: mdl-8575558

ABSTRACT

The immunosuppressant cyclosporin A (Sandimmune) has become the first line treatment for preventing rejection of transplanted organs and for certain autoimmune diseases. The discovery of that drug and its preclinical development are described, and it is shown that most earlier accounts of the history of this compound are, in important respects, incorrect and misleading.


Subject(s)
Cyclosporine/history , Immunosuppressive Agents/history , Cyclosporine/immunology , Cyclosporine/isolation & purification , History, 20th Century , Sesquiterpenes/history , Switzerland
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