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1.
J Nurs Educ ; 38(5): 228-34, 1999 May.
Article in English | MEDLINE | ID: mdl-10438097

ABSTRACT

Preparing culturally competent practitioners is critical, and evaluating the effect of experiences intended to move students toward cultural competence is important. This research study explored the relationship among short-term international nursing clinical immersion experiences, cultural self-efficacy, and cultural competence. A triangulated research design was used to explore the relationship among the variables with 200 senior undergraduate and graduate nursing students from a university in New England. Quantitative analysis found statistically significant differences in the achievement of cultural self-efficacy for the participants who completed the international clinical experiences versus those who remained in the United States. Qualitative analysis, used to further explain the quantitative results, found that the differences were related to international students' ability to overcome their ethnocentrism, experience a transformative perspective about being culturally aware and sensitive, as well as understand and integrate the patients' cultural practices and beliefs into the students' Western health care practices. It became apparent that something other than cultural self-efficacy had occurred for participants in the international immersion experiences. The students believed they had entered the arena of cultural competence. Short-term clinical cultural immersion experiences have relevance for assisting faculty to move nursing students toward an understanding and achievement of cultural competence in ways currently not possible with nonimmersion community cultural experiences.


Subject(s)
Clinical Competence , Cultural Diversity , Transcultural Nursing/education , Adult , Cultural Evolution , Education, Nursing, Baccalaureate/statistics & numerical data , Education, Nursing, Graduate/statistics & numerical data , Female , Humans , Male , Middle Aged , Multivariate Analysis , New England , Self Efficacy , Students, Nursing/psychology , Students, Nursing/statistics & numerical data , Surveys and Questionnaires , Transcultural Nursing/statistics & numerical data
2.
Nucleosides Nucleotides ; 17(5): 925-37, 1998 May.
Article in English | MEDLINE | ID: mdl-9708332

ABSTRACT

A chiral acyclic nucleoside, one in which the ribose carbohydrate has been replaced with a glycerol-based linker, is prepared by glycosylating guanine at the N7-nitrogen. The stereochemically pure derivative is converted to a DMT-protected phosphoramidite for incorporation into DNA sequences. Sequence containing the acyclic N7-dG nucleoside are capable of forming DNA triplexes in which it is likely that the N1-H and N2-amino groups of the N7-dG are involved in recognition of the guanine base in G-C base pairs.


Subject(s)
Guanine , Nucleosides/chemical synthesis , Chromatography, High Pressure Liquid , DNA/chemistry , Glycosylation , Magnetic Resonance Spectroscopy , Models, Chemical
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