ABSTRACT
Introduction: Therapeutic hypothermia (TH) within 6 hours after birth is known to improve both survival and neurodevelopmental outcomes in neonates with hypoxic ischemic encephalopathy (HIE). Meeting this recommended target temperature for neonates who require transport for TH treatment can be complex for various reasons. This study aimed to reduce the time from birth to the initiation of TH and target temperature, thereby increasing the proportion of transported neonates reaching target temperature within 6 hours to >50%. Methods: We evaluated the effect of three quality improvement interventions, including revised transport team processes, outreach education/resources, and the use of a servo-controlled cooling device on land transports. We compared key outcome TH metrics for cohorts before and after implementation. Results: The study team compared baseline data for 77 to 102 neonates born between 2009 and April 2015 (preintervention) and September 2015 and September 2020 (postintervention(s)). We observed reductions in both the time from birth to the initiation of passive cooling (38%) and time to reach target TH temperature (23%), with an increase in the proportion of neonates reaching target temperature by 6 hours of age from 50% to 71%. Conclusions: We used quality improvement methodology to identify key areas for intervention(s) and improvement. Targeted interventions have successfully and consistently improved the timing and delivery of TH to neonates with hypoxic ischemic encephalopathy within the transport environment, with a 20% increase in neonates reaching target temperature by 6 hours of age.
ABSTRACT
Thrombosis is an underlying cause of one in four deaths globally. The International Society on Thrombosis and Haemostasis established the inaugural World Thrombosis Day on October 13, 2014. The World Thrombosis Day campaign aims to 1) highlight the disease burden from thrombosis, 2) increase public awareness of the risks, signs, and symptoms of thromboembolic conditions, 3) empower individuals to discuss their thrombosis risk with their healthcare provider, 4) galvanize organizations across the globe, and 5) advocate for "systems of care" to prevent, diagnose, and treat venous thromboembolism and atrial fibrillation. Public health messages include: "know the risks, signs, and symptoms of blood clots," "potentially fatal blood clots in the veins can be prevented," "atrial fibrillation can be diagnosed by a doctor feeling one's pulse," and "effective strategies for stroke prevention in patients with atrial fibrillation are available." To demonstrate the public health impact of the World Thrombosis Day campaign, we measured campaign reach, size and breadth of our partner network, as well as traditional and digital media impressions. The campaign reached an estimated ≥2.3 billion people globally in 2016. As part of the World Thrombosis Day campaign, approximately 8,200 activities were held globally and our partner network expanded to ≥675 partners across 80 countries in 2016. Social media metrics reached 170 million impressions and traditional media reached 1.9 billion impressions. We appreciate and thank our partners for their contributions and encourage others to support this campaign to reduce thrombosis-related morbidity and mortality worldwide.
