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Ann Vasc Surg ; 21(6): 816-8, 2007 Nov.
Article in English | MEDLINE | ID: mdl-17697765

ABSTRACT

Alport's syndrome is a rare genetic disorder of type IV basement membrane collagen synthesis that typically presents with nephropathy, deafness, and ocular abnormalities. To the best of our knowledge, this is the first report in the world's literature of ruptured thoracoabdominal aortic aneurysm in a young patient with Alport's syndrome and a renal transplant. Hypotheses on an association between collagen disease in Alport's syndrome and aortic aneurysms are discussed.


Subject(s)
Aortic Aneurysm, Thoracic/etiology , Aortic Rupture/etiology , Kidney Transplantation , Nephritis, Hereditary/surgery , Adult , Anastomosis, Surgical , Aortic Aneurysm, Thoracic/diagnostic imaging , Aortic Aneurysm, Thoracic/surgery , Aortic Rupture/diagnostic imaging , Aortic Rupture/surgery , Blood Vessel Prosthesis Implantation , Device Removal , Graft Occlusion, Vascular/surgery , Humans , Male , Nephritis, Hereditary/complications , Tomography, X-Ray Computed , Treatment Outcome
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