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1.
J Chemother ; 20(3): 312-8, 2008 Jun.
Article in English | MEDLINE | ID: mdl-18606585

ABSTRACT

This prospective study assessed the Surgical Site Infection (SSI) rates in General Surgery and the microorganisms isolated. From January 2000 to October 2000, 898 patients were enrolled and electively operated in a General Surgery Clinic in Athens, Greece. Pre-coded questionnaires were used. The diagnosis and surveillance of SSIs was made by the surgeon-investigator who interviewed the patients. Patients were monitored during hospitalization and post-discharge for 30 days. Overall, 402 patients underwent a clean and 496 patients underwent a clean-contaminated operation. A total of 17 SSIs (4.2%) were observed in clean and 64 SSIs (12.9%) in clean-contaminated operations. Microorganisms were isolated in 36 of 65 (55%) of cases that microbiological evaluation was performed. Staphylococcus aureus was the commonest microorganism isolated, followed by Escherichia coli and Pseudomonas aeruginosa. SSI rates were higher than expected and most SSIs, 43 of 81 (53.1%), were diagnosed post-operatively. Post-discharge surveillance of SSIs remains a critical issue. Health care professionals, especially surgeons, should participate in surveillance networks and be aware of the results so to take appropriate action.


Subject(s)
Bacterial Infections/epidemiology , Cross Infection/epidemiology , Surgical Wound Infection/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Anti-Bacterial Agents/therapeutic use , Bacteria/classification , Bacteria/isolation & purification , Bacterial Infections/diagnosis , Bacterial Infections/drug therapy , Cross Infection/diagnosis , Cross Infection/drug therapy , Female , Greece/epidemiology , Humans , Interviews as Topic , Male , Middle Aged , Prospective Studies , Surgical Wound Infection/diagnosis , Surgical Wound Infection/drug therapy , Surveys and Questionnaires
2.
J Antimicrob Chemother ; 61(1): 214-8, 2008 Jan.
Article in English | MEDLINE | ID: mdl-17999981

ABSTRACT

OBJECTIVES: To evaluate the adherence of general surgeons to guidelines for antimicrobial prophylaxis. This study was held from January 2000 until October 2000 in a General Surgery Clinic in a hospital in Athens, Greece. METHODS: Eight hundred and ninety-eight patients were enrolled and operated on electively. Questionnaires concerning demographic data, health status, type of surgery (clean and clean-contaminated) and parameters of antibiotic prophylaxis (antibiotic choice, route, dose, timing of first dose, timing of operative redosing and duration of prophylaxis) were completed. RESULTS: Of the patients, 44.8% underwent a clean surgical operation and 55.2% underwent a clean-contaminated surgical operation. Inguinal hernia repair and laparoscopic cholecystectomy were the commonest operations in each category. Second-generation cephalosporins were the most frequently prescribed antibiotics, in 67%. Although, only 78.5% of procedures required prophylaxis, it was administered in 97.5%, so it was not justified and inappropriately administered in 19%. It was revealed that 100% of patients received antibiotic prophylaxis on time. The choice of antimicrobial agent was appropriate in 70% and the duration of prophylaxis was optimal in 36.3%. The overall compliance rate of surgeons with guidelines for antibiotic prophylaxis was 36.3%. CONCLUSIONS: Adherence to separate aspects of guidelines for surgical prophylaxis has to be improved. The duration of antibiotic prophylaxis was the main parameter of interest. Interventions have to be made about the development, distribution and adoption of adequate guidelines in collaboration with surgeons.


Subject(s)
Antibiotic Prophylaxis , Cephalosporins/therapeutic use , Guideline Adherence , Practice Patterns, Physicians' , Surgery Department, Hospital , Cephalosporins/administration & dosage , Greece , Humans , Practice Guidelines as Topic , Surgical Procedures, Operative
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