ABSTRACT
We describe a case of late PVE in a 78-year-old man that was caused by Stapylococcus hemolyticus and occurred 5 years after aortic valve replacement. This is the first reported case of PVE due to this organism.
Subject(s)
Endocarditis, Bacterial/diagnosis , Staphylococcal Infections/diagnosis , Staphylococcus/isolation & purification , Aged , Aortic Valve , Heart Valve Prosthesis , Humans , MaleABSTRACT
We performed a randomized prospective study of 5-day treatment with topical mupirocin or bacitracin for the elimination of Staphylococcus aureus nasal colonization in healthcare workers (HCWs). Nasal cultures were obtained from 141 HCWs, 37 (26%) of whom showed S. aureus. After 72 to 96 hours of treatment, the organism was eradicated in 15 (94%) of 16 by mupirocin and in 8 (44%) of 18 by bacitracin (P = .0031). Similar efficacy was demonstrated at 30 days. Mupirocin may be more effective than bacitracin for eradication of S. aureus in healthy HCWs.
