ABSTRACT
The epidemiology of hydatid disease in man in England and Wales, based on the data collected between 1981 and 1983 at the Hydatid Reference Laboratory of the Public Health Laboratory Service, is presented. The incidence of hydatid disease was 42 cases per annum, with 2 cases per million population occurring in Wales and 0.2 per million in England. The highest prevalence was in London amongst the immigrant population. The incidence in the indigenous population was 15.5 cases per annum, with 5.6 cases per million occurring in South Powys, parts of South Wales and Herefordshire. The population most at risk is the rural, farming community in that area, but the West Midlands is also an apparent focus of the disease.
Subject(s)
Echinococcosis/epidemiology , Adolescent , Adult , Age Factors , Aged , Animals , Animals, Domestic , Child , Demography , Dogs , Echinococcosis/etiology , England , Female , Humans , Male , Middle Aged , Public Health , Sex Factors , WalesABSTRACT
Albendazole was given orally to sheep with naturally occurring live pulmonary and hepatic cysts. The viability of pulmonary cysts was established before treatment by thoracotomy and needle puncture. Both 10 and 20 mg/kg/day doses were found effective in that no viable protoscoleces were found after six weeks' treatment in either group while untreated controls still had viable cysts. In addition, treated animals showed macroscopic and electron microscopic changes. Bone marrow toxicity probably occurred in two sheep.
Subject(s)
Benzimidazoles/therapeutic use , Echinococcosis, Pulmonary/veterinary , Sheep Diseases/drug therapy , Albendazole , Animals , Echinococcosis, Pulmonary/diagnostic imaging , Echinococcosis, Pulmonary/drug therapy , Echinococcosis, Pulmonary/pathology , Female , Humans , Lung/diagnostic imaging , Lung/ultrastructure , Radiography , Sheep , Sheep Diseases/diagnostic imaging , Sheep Diseases/pathologyABSTRACT
A procedure for the clinical investigation and surgical treatment of cases of coenuriasis in sheep was assessed. The results were based on a series of 62 cases of coenuriasis, of which 58 per cent did not have any palpable skull softening. A useful correlation between the neurological signs and the location of cysts was demonstrated, enabling accurate localisation of cysts in 68 per cent of cases. The surgical technique for the removal of cysts gave a success rate of 74 per cent among the 42 cases selected for surgery, as judged by the complete removal of the cyst and recovery of neurological functions.
