1.
HLA
; 98(3): 233-234, 2021 09.
Article
in English
| MEDLINE
| ID: mdl-34089244
ABSTRACT
We describe here four novel HLA class II alleles, DPA1*01:33, DPB1*1082:01, DPB1*1144:01, and DQA1*01:45, identified in our laboratory following the implementation of next generation sequencing (NGS) for routine high resolution HLA typing of donors and recipients for solid organ transplant and hematopoetic stem cell transplant. The NGS technology has improved our ability to match at all clinically HLA loci and to facilitate the interpretation of allele specific antibody and eplet matching.
Subject(s)
High-Throughput Nucleotide Sequencing , Organ Transplantation , Alleles , HLA Antigens , Histocompatibility Testing
2.
HLA
; 98(2): 177-178, 2021 08.
Article
in English
| MEDLINE
| ID: mdl-33934545
3.
HLA
; 94(2): 157-158, 2019 08.
Article
in English
| MEDLINE
| ID: mdl-31074116
ABSTRACT
HLA-B*27:05:38 differs from HLA-B*27:05:02:01 by 2 mismatches in exon 3, resulting in 2 synonymous mutations.
Subject(s)
Alleles , HLA-B Antigens/genetics , Codon/genetics , DNA/genetics , DNA/isolation & purification , Histocompatibility Testing , Humans , Male , Software
4.
Identification of a novel HLA-C allele, HLA-C*07:778, in an unrelated hematopoietic stem cell donor.
HLA
; 94(2): 161-162, 2019 08.
Article
in English
| MEDLINE
| ID: mdl-31069965
ABSTRACT
HLA-C*07:778 differs from HLA-C*07:01:01:01 by a single nonsynonymous nucleotide substitution at codon 263 (CACâCAG).
