Treatment of lumbosacral radicular pain with epidural steroid injections.

Fifty patients with an average age of 47 years received epidural steroid injections for lumbosacral radicular pain due to disk herniation or spinal stenosis. All patients had failed previous conservative treatment. Mean follow-up was 24 months (range: 12-36 months). Immediately after injection, all 50 patients reported various degrees of relief from leg and back pain. At the last follow-up examination, 68% of patients were asymptomatic, 20% had no change in preinjection radicular symptoms, and 12% had various degrees of relief. No significant correlation was found between pain relief, age, or number of injections. Early pain relief may be anticipated after epidural steroid injections in 80% of patients with radicular symptoms due to disk herniation or spinal stenosis.

Long-term mechanical stability of the impacted morselized graft-cement interface in total joint replacement: an experimental study in dogs.

This experimental study compared the long-term (12 months) mechanical stability of the morselized graft-cement interface with the conventional bone-cement interface in both femoral bones of 10 adult dogs. For mechanical testing, three-point bending and push-out loading tests of composite bone-cement beams were used, while the incorporation of the graft was assessed by serial radiographs. Although the parameters fracture load and interface failure load showed inferior values in the specimens with a morselized graft-cement interface compared to those in specimens with a conventional bone-cement interface, no statistically significant differences were found between groups. Radiographic reconstitution of the lateral femoral cortex was observed in all animals at 3 months while signs of advanced remodeling were apparent at 6 months. These results indicate the long-term mechanical stability of the impacted morselized graft-cement interface is comparable to that of the conventional bone-cement interface created in primary total hip replacements provided the grafted area is protected from early heavy loading.

Epidemiology, demographics, and natural history of congenital hip disease in adults.

This study examined the epidemiology and demographics of congenital hip disease in 468 (660 hips) patients who were examined between 1970 and 1996. In 356 (54%) hips, the diagnosis was secondary osteoarthritis due to congenital hip disease, and in 272 (41%) hips, the diagnosis was idiopathic osteoarthritis. In the remaining 32 (5%) hips, the diagnosis was uncertain. Of the hips with congenital hip disease, 170 (47.7%) hips were dysplastic, 85 (23.9%) had low dislocation, and 101 (28.4%) high dislocation. The majority of patients with congenital hip disease were women (338 [95%] hips). The natural history of the three types of congenital hip disease was studied in 157 patients (202 hips: 102 dysplastic, 42 low dislocation, and 58 high dislocation) who had received no treatment before the initial examination. Average length of follow-up was 17 years. In dysplastic hips, the disease remained undiagnosed until the onset of symptoms at an average age of 34.5 years. In patients with low dislocation, pain had started at an average of 32.5 years due to progressive degenerative arthritis within the false acetabulum. In patients with high dislocation, in the presence of a false acetabulum, pain started at an average age of 31.2 years, while in its absence, pain started at an average age of 46.4 years due to muscle fatigue. These findings suggest dysplasia, low dislocation, and high dislocation in adults are the results of untreated dysplasia, subluxation, and complete dislocation in infancy, respectively.

Pain pattern in multiple vertebral hemangiomas involving non-adjacent levels: report of two cases.

Hemangioma of the bone is a benign tumor usually involving the spine and the bones of the skull and pelvis. It may be either a single lesion or part of a generalized multifocal disease. Multiple lesions involving non-adjacent vertebrae are rare. Two cases of multiple vertebral hemangiomas at non-adjacent levels with different pain patterns are presented at various stages of follow-up in order to emphasize the fact that multiple vertebral hemangiomas may present with different clinical characteristics over a long period of time. The change in the location and pattern of the initially presented pain in both patients suggested the possibility of multiple level involvement. Investigation revealed multiple hemangiomas involving three non-adjacent vertebrae in the first patient and four in the second. We stress the fact that the existence of multiple non-adjacent lesions may remain undiagnosed for a considerable period of time and may be responsible for even longer-term recurrent episodes of pain. Multifocal location of back pain in patients with a known vertebral hemangioma may be considered a relative indication for the presence of multiple non-adjacent level lesions.

Spontaneous interbody fusion after controlled injuries to the spine: an experimental study in rabbits.

To evaluate the rationale of spontaneous spine fusion after a spinal injury, the authors conducted an experimental study that consisted of three types of controlled injuries to a rabbit spine model. The first was injury to the intervertebral disk (type I injury). The second was injury of the intervertebral disk along with injury to one of the adjacent vertebral end plates (type II). In type III injury, both the opposing end plates were injured along with the intervertebral disk. In 38 rabbits, a total of 82 injuries of these three types were inflicted. Twenty-six injuries were of type I (n = 22 rabbits), 26 were type II (n = 24 rabbits), and 30 were type III (n = 26 rabbits). Spontaneous fusion occurred only in type III injuries. From the 30 type III injuries, fusion occurred in 20 (66.6%). For an autofusion to occur, both epiphyseal plates may be injured. In the clinical situation, this observation suggests that a radiographically obscure lesion of both neighboring vertebrae may proceed to autofusion of that spinal segment observed later.

Seven- to 20-year outcome of lumbar discectomy.

STUDY DESIGN: A retrospective, follow-up study. OBJECTIVES: To assess the effects of conventional surgery for lumbar disc herniation over an extended period of time and to examine factors that might correlate with unsatisfactory results. SUMMARY OF BACKGROUND DATA: Although the short-term results of lumbar discectomy are excellent when there is a proper patient selection, the reported success rates in the long-term follow-up studies vary, and few factors have been implicated for an unsatisfactory outcome. METHODS: One hundred-nine patients with surgically documented herniated lumbar disc were analyzed, retrospectively, by an independent observer. Long-term follow-up (mean 12.2 years) was done by a mailed, self-report questionnaire that included items about pain relief in the back and leg, satisfaction with the results, need for analgesics, level of activity, working capacity, and reoperations. Subjective disability was measured by the Oswestry questionnaire. Radiographic review was carried out in 66% of patients. End results were assessed using the modified Stauffer-Coventry's evaluating criteria. Several variables were examined to assess their influence to the outcome. RESULTS: The late results were satisfactory in 64% of patients. The mean Oswestry disability score was 18.9. Of the 101 patients who had primary procedures, 28% still complained of significant back or leg pain. Sixty-five percent of patients were very satisfied with their results, 29% satisfied, and 6% dissatisfied. The reoperation rate was 7.3% (8 patients), about one-third of which was due to recurrent disc herniation. Sociodemographic factors predisposing to unsatisfactory outcome, including female gender, low vocational education, and jobs requiring significant physical strenuousness. Disc space narrowing was common at the level of discectomy, but was without prognostic significance. CONCLUSIONS: The long-term results of standard lumbar discectomy are not very satisfying. More than one-third of the patients had unsatisfactory results and more than one quarter complained of significant residual pain. Heavy manual work, particularly agricultural work, and low educational level were negative predictors of a good outcome. These indicators should be used preoperatively to identify patients who are at high risk for an unfavorable long-term result.

Treatment of high dislocation of the hip in adults with total hip arthroplasty. Operative technique and long-term clinical results.

The clinical results of eighty-four total hip arthroplasties performed through a transtrochanteric approach in sixty-seven patients who had a high dislocation of the hip (the femoral head completely out of the acetabulum), from 1976 to 1994, were reviewed. The acetabular component was placed in the true acetabulum and the femur was shortened at the level of the femoral neck, along with release of the psoas tendon and the small external rotators, in order to facilitate reduction of the components and to avoid neurovascular complications. Eleven hip prostheses (13 per cent) failed at a mean of 6.4 years (range, two months to sixteen years) postoperatively; the failure was due to aseptic loosening of both components in four hips, aseptic loosening of the stem only in three, late infection in three, and malpositioning of the acetabular component that caused recurrent dislocations in one. The other seventy-three hips were functioning well at the latest follow-up examination, two to twenty years (mean, 7.1 years) postoperatively. The overall cumulative rate of success was 92.4 per cent (95 per cent confidence interval, 89.5 to 95.3 per cent) at five years and 88.0 per cent (95 per cent confidence interval, 82.2 to 93.8 per cent) at ten years. We believe that this operative technique of total hip arthroplasty is effective for the treatment of the difficult condition of high dislocation of the hip.

Congenital hip disease in adults. Classification of acetabular deficiencies and operative treatment with acetabuloplasty combined with total hip arthroplasty.

We describe three distinct types of congenital hip disease in adults. The first type is dysplasia, in which the femoral head is contained within the original true acetabulum. The second type is low dislocation, in which the femoral head articulates with a false acetabulum, the inferior lip of which contacts or overlaps the superior lip of the true acetabulum, giving the appearance of two overlapping acetabula. The third type is high dislocation, in which the femoral head has migrated superoposteriorly and there is no contact between the true and the false acetabulum. We describe and classify the acetabular abnormalities and deficiencies found with these three types. If the anterior, posterior, and superior aspects of the acetabular component cannot be covered during a total hip arthroplasty because of a deficient acetabulum in an adult who has congenital hip disease, we advocate and acetabuloplasty technique (which we have named a cotyloplasty) that involves medial advancement of the acetabular floor by the creation of a controlled comminuted fracture of its medial wall, autogenous bone-grafting, and the implantation of a small acetabular component with cement. This procedure was performed in sixty-six patients (eighty-six hips). Forty-nine of the hips had a high dislocation, thirty-one had a low dislocation, and six were dysplastic. Two to fifteen years (mean, seven years) after the operation, the clinical and radiographic results were satisfactory. Only two acetabular components needed to be revised for aseptic loosening, at 5.3 and 7.5 years postoperatively. Moreover, the cumulative success rate for the acetabular components was 100 percent at five years and 93.2 percent at ten years.

The anterior inferior angle fracture of a lower cervical vertebra.

Thirty-eight cases of a "tear drop" fracture of the lower cervical spine treated in our department during the last 20 years are reported. They represent 8.3% of all cervical injuries. We classified our cases into four types with regard to the extent of the bony lesion and the resulting posterior displacement of the vertebral body. Posterior displacement is of paramount importance. Neurological lesions were present in 52.6% of the patients, and they were related to the type of injury. Five patients died, and 33 were followed up for a mean period of 10 years. Five patients were operated on. All patients with a complete neurological lesion remained unchanged irrespective of the type of treatment. Incomplete neurological lesions showed a better tendency to recover after surgical treatment. Types III and IV are the more serious lesions, and they represent an absolute indication for surgical treatment. Type I is more benign and, if treated properly, has a good prognosis similar to type II.

Results of lumbar discectomy: a study using 15 different evaluation methods.

Ninety-two patients who had undergone a primary excision of a lumbar disc were evaluated using 15 different criteria that evaluate the surgical outcome 2-15.5 years (average 8.8 years) following operation. The satisfactory results ranged from 62% to 84%. Criteria which relied on the subjective opinion of the patient gave the best results, while on the contrary the worst results were those that relied on functional criteria, such as return to work, return to previous employment, general activity level and need of further treatment. This variability in results observed with the same group of patients depends to a great extent on the nature of criteria used as well as on the design of those criteria. The study concludes that the reported outcomes for lumbar spinal surgery are influenced by the selection of the criteria used for the assessment of the end results.

Fifteen years' experience with Charnley low-friction arthroplasty.

In the years from 1973 to 1986, 359 low-friction hip arthroplasties were performed by the precise Charnley technique in 310 patients. Three hundred seventeen hips were reexamined both clinically and roentgenologically. Clinical evaluation was performed according to follow-up time, separating the total number of hips into three groups. In Group A, 78.49% of the reevaluated hips remained asymptomatic ten to 14 years postoperatively, a percentage that has risen to 92.02% in Group B (studied five to nine years postoperatively) and 98.38% in Group C (studied one to four years postoperatively). The infection rate was 9.6% in Group A hips, 4.7% in Group B hips, and inconsequential in Group C hips. The roentgenographic study included 96 asymptomatic hips with a follow-up period of six to 11 years (mean, 8.3%). A radiolucent line was present in the acetabulum in 40.6% of cases; cortical hypertrophy at the tip of the stem was present in 48.8% of cases. Cup wear of more than 1 mm was measured in 41.3% of hips and was correlated with longer follow-up times and younger patient age. The results are encouraging for the continuation of arthroplasty by this method.

Fractures of the dens and risk of pseudarthrosis.

This study deals with 49 fractures of the dens treated at the Orthopedic Department of Athens University during the past 17 years. These fractures represent 14.2% of all cervical fractures treated during the same period at our department. Forty-one cases have been reviewed and analyzed, the average follow-up time being 10 years (1-16). Pseudarthrosis was found to be present in seven cases (17%), and its relationship to different factors was examined. The type of fracture and particularly the direction of the fracture line were found to be major factors leading to pseudarthrosis. Many other factors, such as displacement, traction, the stability obtained, the presence of associated injuries, and the time elapsed till treatment was started, as well as the age of the patients, seem to play--alone or in combination--important roles in the development of pseudarthrosis. These factors have been classified according to their importance and graded. With a total of 10 points or more a dens fracture is characterized as a fracture "at risk of pseudarthrosis", i.e., a fracture with a higher possibility of developing a pseudarthrosis. This knowledge may contribute to proper and earlier management of such an injury.

Low friction arthroplasty for old untreated congenital dislocation of the hip.

We report the replacement of 42 hips in 34 adults with untreated congenital dislocation. We used Charnley low friction implants, cementing the cup at the level of the true acetabulum after deepening and enlarging it by our own technique of cotyloplasty. Results were evaluated in 38 hips after a mean of 5.5 years. All the patients showed marked improvement, with no infection and, as yet, no late revision. The technical difficulties of the operation and the complications are discussed.