ABSTRACT
Extensive combined resections were made on 190 of 705 patients operated upon for lung cancer. The results have shown a prognostic value of the factor of variability of resections for immediate results. Long-term results were better in patients with highly differentiated cancers and without a metastatic involvement of the regional lymphatic system. Favourable results with 5-year survival (20.2%) point to the expedience of the extensive combined resections in patients with the long-neglected stages of lung cancer.
Subject(s)
Adenocarcinoma/surgery , Carcinoma, Squamous Cell/surgery , Carcinoma/surgery , Lung Neoplasms/surgery , Pneumonectomy/methods , Adenocarcinoma/mortality , Adult , Aged , Carcinoma/mortality , Carcinoma, Squamous Cell/mortality , Female , Humans , Lung Neoplasms/mortality , Lymphatic Metastasis , Male , Middle Aged , Pneumonectomy/statistics & numerical data , Postoperative Complications/mortality , PrognosisABSTRACT
Results of a complex clinico-functional examination of 48 patients after resection for lung cancer 8-10 years ago are presented. The satisfactory pumping function of the heart was revealed with practically normal volumes of the cardiac output. Among patients subjected to resection of a lobe of the lung two groups were determined: with relatively satisfactory parameters of the function of external respiration and blood circulation and with a pronounced degree of strain of the functioning of these systems.
Subject(s)
Lung Neoplasms/surgery , Lung/physiopathology , Pneumonectomy , Aged , Humans , Lung Neoplasms/physiopathology , Male , Postoperative Period , Respiratory Function TestsABSTRACT
The article generalizes an experience with surgical treatment of lung cancer of low-differentiated structures in 108 patients. Extended and combined resections of the lung in such patients were shown to be expedient. From 83 patients who had had bronchial biopsy in the process of preoperative examination 35 patients (42.2%) had results of histological examinations of the biopsy and operative materials which did not coincide. Extended and combined resections for lung cancer of low-differentiated structure gave 5-year survival in 15.6% of the patients.
Subject(s)
Adenocarcinoma/surgery , Carcinoma, Non-Small-Cell Lung/surgery , Carcinoma, Small Cell/surgery , Carcinoma, Squamous Cell/surgery , Lung Neoplasms/surgery , Pneumonectomy/methods , Adenocarcinoma/mortality , Adenocarcinoma/pathology , Adult , Aged , Biopsy , Bronchoscopy , Carcinoma, Non-Small-Cell Lung/mortality , Carcinoma, Non-Small-Cell Lung/pathology , Carcinoma, Small Cell/mortality , Carcinoma, Small Cell/pathology , Carcinoma, Squamous Cell/mortality , Carcinoma, Squamous Cell/pathology , Female , Humans , Lung/pathology , Lung Neoplasms/mortality , Lung Neoplasms/pathology , Male , Middle Aged , Neoplasm Staging , Postoperative Complications/epidemiologyABSTRACT
The effect of vasopressin on learning, habituation and habit recovery in rat before and after electrolytic ablation of locus coeruleus, nuclei dorsalis et medialis raphe and pars compacta substantiae nigrae was studied by behavioural methods. The rats were learned with positive reinforcement in a T-shaped maze and with negative reinforcement in a U-shaped maze. It was found that improvement of trace consolidation and acceleration of learning were in many cases dependent on the activity level of the dophaminergic, noradrenergic and to a lesser degree on that of serotoninergic brain systems.
