[Lichen planus-like eruption. Case report]. / Eruptie lichenoida postmedicamentoasa.

Cutaneous adverse drug reactions are among the most common adverse drug reactions. Thise reactions to drugs can comprise a broad spectrum of clinical and histopathological features, with an important capacity to mimic numerous dermatological diseases, making the diagnose very difficult. We present the case of a patient, under immunomodulating treatment (TNFalpha antagonist and leflunomide), with a muco-cutaneous lichen planus-like eruption.

[Postinfarction left ventricular saccular aneurysm]. / Anevrism sacular gigant al ventriculului stâng, postinfarct.

Postinfarction ventricular aneurysms may be either true or false, each with apparently definite diagnostic criteria on imaging techniques. We present the case of a 69 year-old male admitted to our hospital 6 weeks after an acute anterior myocardial infarction, for progressive exertional dyspnea. Transthoracic echocardiography demonstrated a large cystic cavity, 10 cm in diameter, communicating with the left ventricle's apex through an orifice of 5 cm diastolic diameter. The echocardiographic diagnosis was of a large, saccular aneurysm. Contrast ventriculography confirmed the existence of a large cavity connected to the apex of the left ventricle, 12 cm in diameter, with sluggish flow of contrast within it and features suggestive of pseudoaneurysm. The patient was referred for surgery because of continued symptoms and a preoperative diagnosis of either a large ventricular aneurysm or pseudoaneurysm. At the time of surgery a true aneurysm was found. We present this case because the rarity of a saccular configuration of a postinfarction left ventricular aneurysm, because of the unusual large size of it and to point on the possible disagreement between the conclusions of imaging modalities in differentiating a true from a false aneurysm.

[Marjolin's ulcer on burn scar, a curable but neglected disease]. / Ulcerul Marjolin dezvoltat pe cicatrici postcombustionale--afectiune vindecabila, dar neglijata.

We discuss 9 consecutive carcinomas developed on postburn scars. Our interest was focused on surgery, recurrence, metastasis and long-term survival. The delay between burn trauma and the first clinical manifestation was 25-63 years. The most common localisation was in the limbs (10). Two cases presented with visceral metastasis. We performed either wide excision and grafting (5) or amputation (5). From the anatomo-pathological stand point we encountered 8 SCC and 1 BCC. In 6 cases we had no local recidive or metastasis. One presented a local recidive. There were two deaths--lung metastasis and "spontaneous" rupture of invaded axillary artery. The Marjolin's ulcer has a low incidence because of the patient's poor education. The prophylactic attitude is optimal. We favour early excision--grafting of the deep burns, long-term follow-up, excision and grafting of unstable areas (joint area, depigmented regions, chronic ulcers). The optimal surgical technique is excision followed by skin grafting since it allows early detection of the recurrence.