ABSTRACT
BACKGROUND: Charcot neuropathic arthropathy is a debilitating, rapidly destructive degenerative joint disease that occurs in diabetic, neuropathic midfoot. Clinicoradiologic assessment for Charcot neuropathic arthropathy previously relied on Eichenholtz stage. There is limited histopathologic data on this entity. We wanted to independently develop a histopathologic scoring system for Charcot neuropathic arthropathy. DESIGN: Retrieval of surgical pathology midfoot specimens from Charcot patients (2012-2019) were analyzed to evaluate joint soft tissue and bone. Considering progression from large (≥half 40× hpf) to small (Subject(s)
Arthropathy, Neurogenic/pathology
, Diabetic Foot/surgery
, Foot/physiopathology
, Peripheral Nervous System/blood supply
, Adult
, Aged
, Aged, 80 and over
, Amputation, Surgical/methods
, Arteriolosclerosis/complications
, Arthropathy, Neurogenic/classification
, Arthropathy, Neurogenic/etiology
, Arthropathy, Neurogenic/surgery
, Diabetic Foot/complications
, Diabetic Neuropathies/complications
, Disease Progression
, Female
, Foot/blood supply
, Foot/innervation
, Humans
, Male
, Middle Aged
, Peripheral Nervous System/pathology
, Research Design/standards
