Uterine sarcoidosis potentially associated with interferon-alpha use for chronic hepatitis C infection.

BACKGROUND: A regimen including interferon-alpha has become the standard of care in the treatment of chronic hepatitis C over the last decade. One rare adverse effect associated with the use of interferon-alpha is a granulomatous pulmonary reaction. CASE: A unique case of uterine sarcoidosis associated with the use of interferon-alpha for chronic hepatitis C infection is presented. CONCLUSION: Gynecologists should be aware of a potential association between interferon-alpha therapy and granulomatous reactions occurring not only in the lung but also in the female genital tract.