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Br J Oral Maxillofac Surg ; 25(1): 45-8, 1987 Feb.
Article in English | MEDLINE | ID: mdl-2948543

ABSTRACT

The levels of metronidazole in rat serum and mandibular bones was measured 2, 5 and 8 h after oral administration of three doses of 200 mg/kg. Effective levels of the drug in serum and mandible were found at all time intervals as well as a higher concentration in mandible than in serum.


Subject(s)
Mandible/metabolism , Metronidazole/blood , Administration, Oral , Animals , Metronidazole/administration & dosage , Metronidazole/metabolism , Rats , Rats, Inbred Strains , Time Factors
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