Subject(s)
Hyperpigmentation , Neoplasms , Humans , Adolescent , Hyperpigmentation/diagnosis , Hyperpigmentation/pathologyABSTRACT
Plexiform neurofibromas are benign tumors originating from peripheral nerve sheaths, generally associated with Neurofibromatosis Type 1 (NF1). They are diffuse, painful and sometimes locally invasive, generating cosmetic problems. This report discusses an adolescent patient who presented with an isolated, giant plexiform neurofibroma on her leg that was confused with a vascular lesion due to its clinical aspects. Once the diagnosis was confirmed by surgical biopsy, excision of the lesion was performed with improvement of the symptoms.
Subject(s)
Neurofibroma, Plexiform/pathology , Skin Neoplasms/pathology , Vascular Diseases/pathology , Adolescent , Biopsy , Diagnosis, Differential , Female , Humans , Leg/blood supply , Leg/pathology , Magnetic Resonance Imaging , Neurofibroma, Plexiform/diagnostic imaging , Skin Neoplasms/diagnostic imaging , Vascular Diseases/diagnostic imagingABSTRACT
Abstract Plexiform neurofibromas are benign tumors originating from peripheral nerve sheaths, generally associated with Neurofibromatosis Type 1 (NF1). They are diffuse, painful and sometimes locally invasive, generating cosmetic problems. This report discusses an adolescent patient who presented with an isolated, giant plexiform neurofibroma on her leg that was confused with a vascular lesion due to its clinical aspects. Once the diagnosis was confirmed by surgical biopsy, excision of the lesion was performed with improvement of the symptoms.
Subject(s)
Humans , Female , Adolescent , Skin Neoplasms/pathology , Vascular Diseases/pathology , Neurofibroma, Plexiform/pathology , Skin Neoplasms/diagnostic imaging , Vascular Diseases/diagnostic imaging , Biopsy , Magnetic Resonance Imaging , Neurofibroma, Plexiform/diagnostic imaging , Diagnosis, Differential , Leg/blood supply , Leg/pathologyABSTRACT
Polyarteritis nodosa is a rare vasculitis in children characterized by necrotizing inflammation in small and medium size arteries. It is classified into systemic and cutaneous PAN according to the presence of systemic symptoms or visceral involvement. We describe the case of a 14-year-old girl with cutaneous Polyarteritis nodosa with an atypical clinical presentation.
Subject(s)
Polyarteritis Nodosa/pathology , Skin/pathology , Adolescent , Biopsy , Female , Humans , Necrosis , Subcutaneous Fat/pathologyABSTRACT
Polyarteritis nodosa is a rare vasculitis in children characterized by necrotizing inflammation in small and medium size arteries. It is classified into systemic and cutaneous PAN according to the presence of systemic symptoms or visceral involvement. We describe the case of a 14-year-old girl with cutaneous Polyarteritis nodosa with an atypical clinical presentation.
.Subject(s)
Humans , Female , Adolescent , Polyarteritis Nodosa/pathology , Skin/pathology , Biopsy , Subcutaneous Fat/pathology , NecrosisABSTRACT
Primary cutaneous nocardiosis is an infrequent opportunistic infection that mainly affects immunodepressed hosts. We describe two immunocompetent patients who exhibited two clinical forms of cutaneous nocardiosis, a mycetoma from walking barefoot in contaminated water and in the case of the other patient a lymphocutaneous form on the basis of a stabbing-cutting injury. In both cases the tests performed ruled out any immunodeficiency, particularly chronic granulomatose disease, since nocardiosis is regarded as an infection that acts as a marker for that illness. Treatment with cotrimoxazole led to the total healing of the lesions in both patients.
