ABSTRACT
Results obtained with a potentiometric analyzer, NOVA 1, specific for sodium and potassium, were compared with those by flame photometry. Both instruments showed linearity within a physiological range of sodium and potassium concentrations and had similar precisions. Volume displacements from addition of albumin or Intralipid to aqueous samples yielded the predicted lower flame-photometric results because of the relative decrease in sample water. There may be a small interaction between sodium and albumin. Physiological measurements on plasma from uremic patients showed no change after dialysis that could be ascribed to a decrease in interaction of these ions with creatinine and urea. Potentiometric values for sodium and potassium did not differ significantly, whether measured in cerebrospinal fluid or in the corresponding plasma. Results for urine were the same potentiometrically and by flame photometry.
Subject(s)
Potassium/blood , Sodium/blood , Uremia/blood , Humans , Potassium/cerebrospinal fluid , Potassium/urine , Potentiometry , Reference Values , Sodium/cerebrospinal fluid , Sodium/urine , Spectrophotometry , Uremia/cerebrospinal fluid , Uremia/urineABSTRACT
Renal failure after an overdose of chlorprothixene has been attributed to a direct nephrotoxic effect of the drug. We report a carefully investigated case. No evidence of specific nephrotoxicity was revealed and we suggest that the renal failure is due to ischaemia during a transitory syncope, a well known side-effect of chlorprothixene.
Subject(s)
Acute Kidney Injury/chemically induced , Chlorprothixene/poisoning , Acute Kidney Injury/physiopathology , Adult , Humans , Kidney/drug effects , Male , Suicide, AttemptedABSTRACT
An evaluation of the extent of rehabilitation of 512 Danish dialysis and transplant patients, based on a questionnarie, has been carried out. All transplanted patients and dialysis patients and dialysis patients with only slightly limited working capacity before treatment experienced an improvement, whereas disabled dialysis patients did not experience major changes. Sixty per cent of the patients receive disablement pension and the allotment of pension early in the course of treatment is suspected to be one of the main reasons for the low degree of vocational rehabilitation.
Subject(s)
Kidney Diseases/rehabilitation , Kidney Transplantation , Renal Dialysis , Absenteeism , Adult , Denmark , Educational Status , Female , Humans , Kidney Diseases/surgery , Kidney Diseases/therapy , Male , Middle Aged , Transplantation, Homologous , Work Capacity Evaluation , Workers' CompensationABSTRACT
57 dialysis patients, 29 of whom had been exposed to hepatitis in 1968-69, were re-examined for hepatitis B antigen (HB-Ag) and antibody (HB-Ab) by means of radioimmunoassay (RIA) and counter immunoelectrophoresis (CIE). Infected patients were followed for five years. Compared to CIE, RIA did not detect additional HB-Ag-positive patients, but antibody could persistently be detected in seven out of fifteen patients previously supposed to have escaped infection. tnine surviving HB-Ag-positive transplant patients remained carriers for 50-72 months. None developed clinical signs of chronic hepatic failure.
