ABSTRACT
The novel allele HLA-A*03:275N differs from HLA-A*03:01:01:01 by 1 nucleotide substitutions in exon 2.
Subject(s)
Exons , HLA-A3 Antigen/genetics , Mutation, Missense , HumansABSTRACT
The novel allele DQA1*01:15N differs from DQA1*01:03:01:01 by 1 nucleotide substitutions in exon 2.
Subject(s)
Alleles , HLA-DQ Antigens/genetics , Humans , ItalyABSTRACT
The novel DRB1*01:16 allele differs for G to T substitution at position 595 from DRB3*01:01P.
Subject(s)
Alleles , HLA-DRB3 Chains/genetics , Hematopoietic Stem Cell Transplantation , Point Mutation , Amino Acid Substitution , Base Sequence , Child , Cloning, Molecular , Codon , Exons , Family , Genotype , HLA-DRB3 Chains/immunology , Histocompatibility Testing , Humans , Italy , Male , Molecular Sequence Data , Sequence Alignment , Sequence Analysis, DNA , Transplant RecipientsABSTRACT
The new allele, officially named HLA DRB1*14:129, differs from HLA DRB1*14:54 in exon 2.
Subject(s)
Alleles , HLA-DRB1 Chains/genetics , Point Mutation , Base Sequence , Exons , HLA-DRB1 Chains/immunology , Histocompatibility Testing , Humans , Molecular Sequence Data , Stem Cell Transplantation , Tissue DonorsABSTRACT
HLA-A*03:143 has one nucleotide change from A*03:01: 01:01 at nt 406 from G to C, resulting in an amino acid change at codon 112 of exon 3 from Gly to Arg.
Subject(s)
HLA-A3 Antigen/genetics , Alleles , Amino Acid Substitution , Base Sequence , DNA/genetics , Exons , Female , Genotyping Techniques , Haplotypes , Histocompatibility Testing , Humans , Italy , Male , Molecular Sequence Data , Pedigree , Polymorphism, Single Nucleotide , Sequence Homology, Nucleic AcidABSTRACT
The novel HLA-C allele C*06:58 shows one nucleotide change from C*06:02:01:01 at nt 366 from G to A, resulting in an amino acid change at codon 98 of exon 3 from Met to Ile.
Subject(s)
Alleles , Amino Acid Substitution , Exons/genetics , HLA-C Antigens/genetics , Family , Female , Humans , Italy , Male , Sequence Analysis, DNAABSTRACT
The novel allele HLA-C*16:07:02 differs from HLA-C* 16:07:01 by a silent nucleotide substitution at codon 220 (TAC â TAT).
