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Am J Emerg Med
; 44: 262-266, 2021 06.
Article
in English
| MEDLINE
| ID: mdl-32278569
ABSTRACT
Sympathetic crashing acute pulmonary edema (SCAPE) describes the most severe presentation of acute heart failure (AHF). Immediate intervention is required to prevent hemodynamic decompensation and endotracheal intubation. Although high-dose nitroglycerin (>100 µg/min) has been described for this clinical scenario in limited case reports, the concern for adverse effects such as hypotension and syncope limit providers comfortability in initiating nitroglycerin at these doses. Described here is a case series of four patients who safely and effectively received high-dose nitroglycerin infusions for the management of SCAPE.
Subject(s)
Heart Failure/drug therapy , Nitroglycerin/administration & dosage , Pulmonary Edema/drug therapy , Vasodilator Agents/administration & dosage , Acute Disease , Aged , Female , Heart Failure/complications , Heart Failure/diagnosis , Humans , Infusions, Intravenous , Male , Middle Aged , Pulmonary Edema/diagnosis , Pulmonary Edema/etiology , Syndrome
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