ABSTRACT
Hepatitis E virus (HEV) is a common cause of acute hepatitis worldwide and is endemic in Europe, including Denmark. Several non-liver manifestations have been apparent, the most important of which is neurological, including neuralgic amyotrophy and Guillain-Barré syndrome as summarised in this review. Certain neurological presentations and patients with unexplained mild to moderate increase in liver enzymes, should lead to the consideration of a HEV-related condition. Many research questions regarding HEV-related neurological injury remain unanswered and need further investigation.
Subject(s)
Brachial Plexus Neuritis , Guillain-Barre Syndrome , Hepatitis E virus , Hepatitis E , Nervous System Diseases , Guillain-Barre Syndrome/diagnosis , Guillain-Barre Syndrome/etiology , Hepatitis E/complications , Hepatitis E/diagnosis , Hepatitis E/epidemiology , Humans , Nervous System Diseases/etiologyABSTRACT
Reversible cerebral vasoconstriction syndrome is caused by narrowing of cerebral arteries. The cardinal symptom is relapsing acute-onset headache also known as thunderclap headache, which may be accompanied by neurologic deficits. This is a case report of a 61-year-old woman with CT angiography-verified reversible cerebral vasoconstriction syndrome. We discuss the diagnostic work-up, i.e. lumbar puncture including test for xanthochromia and important brain imaging, differential diagnoses and treatment of the most important causes of thunderclap headache.
