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3.
Article in English | MEDLINE | ID: mdl-6106028

ABSTRACT

Blood group [ABO system] distribution was analysed in 245 children with complications after smallpox vaccination. One hundred and thirty-two children had neurological and 113 and skin or mucosal complications. 41.6% of the children were blood-group A or AB. 58.4% were blood group O or B, which was not a significant difference from the normal population [44.7%---48.7% and 51.0%---55.9%, respectively]. The analysis did not show in persons possessing blood groups A or AB an enhanced susceptibility to complications following antismallpox immunization or to particularly severe clinical forms of these complications. Immunological advantages in persons with blood group O or B were not found either.


Subject(s)
ABO Blood-Group System , Smallpox Vaccine/adverse effects , Child , Child, Preschool , Encephalomyelitis, Acute Disseminated/etiology , Female , Humans , Infant , Isoantibodies/immunology , Male , Neutralization Tests , Skin Manifestations , Vaccination , Vaccinia virus/immunology
5.
Zh Mikrobiol Epidemiol Immunobiol ; (11): 73-8, 1979 Nov.
Article in Russian | MEDLINE | ID: mdl-42243

ABSTRACT

The virological examination of 1365 samples taken from 469 children vaccinated against smallpox revealed considerable differences in the frequency and the time of vaccinia virus detection in different clinical forms of postvaccinal pathology as compared with uncomplicated vaccinal process. During the postvaccinal period taking its normal course vaccinia virus was isolated from 7.3% of children only from the pharynx till day 8 following vaccination. In generalized and creeping vaccinia the virus was isolated from 71.4% of children, in postvaccinal encephalitis from 57.1% of children, in vaccinal angina frove-mentioned complications vaccinia virus was detected in the samples obtained from the patients till days 24, 35, 15 and 24 respectively. The etiopathogenetic role of vaccinia virus in a number of postvaccinal complications is discussed.


Subject(s)
Smallpox Vaccine/adverse effects , Smallpox/prevention & control , Vaccination/adverse effects , Vaccinia virus/isolation & purification , Child, Preschool , Encephalomyelitis, Acute Disseminated/microbiology , Glomerulonephritis/microbiology , Humans , Hypersensitivity/microbiology , Infant , Kaposi Varicelliform Eruption/microbiology , Stevens-Johnson Syndrome/microbiology , Vaccinia/microbiology , Vaccinia virus/pathogenicity
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