[Feto-placental system in diabetes mellitus and hydramnios]. / Feto-platsentarnaia sistema pri sakharnom diabete i mnogovodii.

The fetoplacental system of 132 women with diabetes mellitus and 85 healthy women was studied during the third pregnancy trimester. Blood estradiol and urinary estriol levels were found-reduced in the diabetics, particularly in those with insulin-dependent diabetes. Blood progesterone and oxytocinase levels were found unchanged. These parameters lowered in diabetic glomerulosclerosis. If pregnant diabetics develop hydramnion, their blood estradiol, progesterone, prolactin, and oxytocinase levels increased.

[The hypothalamo-hypophyseo-ovarian systems in rats after deafferentiation of the mediobasal hypothalamus]. / Gipotalamo-gipofizarno-ovarial'naia sistema u krys posle deafferentatsii medio-bazal'nogo gipotalamusa.

Complete surgical deafferentation of the medio-basal hypothalamus (MBH) in rats entails suppression of the oestrus cycle as well as a decrease of luteinizing hormone, estrogens and progesterone release into the blood due to a sharp fall of the luliberine content in the median eminence and arquate nuclei. No connection was revealed between the character of oestrus disturbances and the extent of damage or isolation of the arquate, ventromedial, supraoptic and paraventricular nuclei and the amount of Homori-positive neurosecreted in the MBH. In development of permanent diestrus the MBH isolation was more complete than in the preservation of irregular cycle. The luliberine seems to be produced mainly in the anterior hypothalamus of rats whereas the MBH alone fails to maintain even its tonic secretion. Even in complete surgical isolation of the MBH, separate fibers of the luliberinergic cells penetrate into the MBH maintaining there a certain amount of luliberin and preserving synthesis of the luteinizing hormone in the hypophysis with its decreased release into the blood.

[Hormonal interrelations in the hypophyseal-ovarian system in heifers during prostaglandin F2-alpha-induced estrus]. / Gormonal'nye vzaimootnosheniia v sisteme gipofiz-iaichniki u telok v period éstrusa, indutsirovannogo prostaglandinom F2 alpha.

Study of prostaglandin F2 alpha action, synchronizing the estrus, in experiments on heifers demonstrated that Estrumeit (made by ICI, Great Britain), rostaglandin F2 alpha drug, in a dose of 500 micrograms was an active luteolytic factor, leading to the corpus luteum regress, determined by a fall in the progesteron level in the peripheral blood. During the estrus induction there was a short-term elevation in production and excretion of testosterone, this pointing to the prostoglandins participation in the activation of the androgenic ovarian function. Prolactin hyposecretion was shown to be a necessary condition for the realization of general biological processes for the occurrence of estrus.

[Ineffectiveness of the back cross method in selecting hemp for heterosis]. / O neéffektivnosti metoda vozvratnykh skreshchivanii v selektsii konopli na geterozis.

In the back crossings the heretability caused by the additive effect of the genes predominates. The selection on the characters controlled by the additive genes leads to the homozygosis increase of the population and to the reduced vitality of the plants. The repeated crossing of the heterozygous hybrid plants with the parental form homozygous according to the recessive gene increases the quota of the genes of the latter. It results in the intermediate type of inheritance for all the elements of the back crossing hybrids productivity.

[Cortical influences on thyroid and sex gland function in neurotic dogs]. / Kortikal'nye vliianiia na funktsiiu shchitovidnoi i polovykh zhelez pri éksperimental'nom nevroze u sobak

Disturbances of higher nervous activity charactetized by the development of an experimental neurosis were elicited in three male dogs by means of functional influences. This was accompanied by an increase, decrease or no change in the level of total thyroxine in the blood with greater fluctuations of its content on different days. An euthyreoid state persisted in the dogs throughout all periods of the neurosis, which is testified by the absence of changes of the free thyroxine coefficient. In the first three to four weeks of the experimental neurosis the testosterone content in the blood plasma was enhanced, its level not correlating with the variations of thyroxine content in the blood.

[Correlation of the production of gonadotropic and sex hormones in boys and girls during sex maturation]. / Sootnoshenie produktsii gonadotrophykh i polovykh gormonov u mal'chikov i devochek v period polovogo sozrevaniia

PIP: There is an early period of puberty in boys at the age of 10 to 13, accompanied by an increase in the level of follicle stimulating hormone and a low secretion of luteinizing hormone and testosterone, with no secondary sexual signs. The beginning of an increase in the luteinizing hormone and testosterone concentration in boys coincides with the development of secondary sexual signs. The stabilization of the level of luteinizing hormone takes place in boys already at the 2nd degree of the sexual development. The secretion of luteinizing hormone at this point corresponds already to the normal level in adult men. The level of testosterone in the blood continues to increase and does not reach its definitive level until after the age of 17, or at the 5th degree of sexual development. Like in boys, the increase of the follicle stimulating hormone in girls precedes the increase of the luteinizing hormone secretion. The beginning of the increase in the follicle stimulating hormone coincides with an increase in the level of estrogens and testosterone in the blood, and with the appearance of secondary signs of sexual maturation. The increase of the luteinizing hormone secretion takes place later in girls than in boys and is accompanied by a new and significant increase in the level of estrogens in the blood. At the 2nd degree of sexual development, the level of testosterone in the blood of girls is substantially higher than at the other stages.^ieng

[Hormonal function of the ovaries in women with breast hyperplasia]. / Gormonal'naia funktsiia iaichnikov u zhenshchin pri giperplazii molochnykh zhelez

In females showing fibrous-cystic mastopathy and fibroadenomatosis of mammary glands a specific form of progesterone insufficiency- relative one, was revealed, a high persistantly maintained level of urine pregnandiol and blood progesterone in a luteal phase (indicating a high hormonal activity of the corpus luteum) being observed. But luteal transformations were insignificant both in endometrium and vaginal epithelium, a moderate hypoestrogenemia being noted in the first phase and increased estrogen excretion- in the second phase of the cycle.