ABSTRACT
An experimentally-clinical assessment of reparative regeneration collagenation of gastroduodenal anastomosis was made. The anastomoses were formed by different ways: the inverted twin-row (classical) and everting one-row anastomosis. It was stated, that tissues repair on suture-line of the everting anastomosis took place faster and better (on a type of primary intention with wound epithelization on 3-5 days). It was specified by comparatively smaller biophysical metabolic disorders in regenerative structures and characteristics of tissues adaptation (broad zone of anatomic alignment of submucous layer of gastric stump and muscular coat of duodenum stump) in anastomosis zone.
Subject(s)
Anastomotic Leak/prevention & control , Gastrectomy , Gastroenterostomy , Stomach Ulcer/surgery , Surgical Wound Infection/prevention & control , Adult , Animals , Dogs , Duodenum/surgery , Female , Gastrectomy/adverse effects , Gastrectomy/methods , Gastroenterostomy/adverse effects , Gastroenterostomy/methods , Humans , Intraoperative Care/methods , Male , Middle Aged , Models, Animal , Monitoring, Physiologic , Stomach/surgery , Suture Techniques , Treatment Outcome , Wound HealingABSTRACT
Billroth I gastric resection with end-to-end gastroduodenal anasthamosis was carried out to 73 patients with complicated duodenal ulcers using new technologies: duodenal mobilization only to the level of ulcer defect, the use of one-row (uninterrupted or nodal) everted suture with adaptation zone of submucous base of gastric stump and muscle coat of duodenal stump. Good early and long-term results were achieved.
Subject(s)
Duodenal Ulcer/surgery , Gastroenterostomy/methods , Peptic Ulcer Perforation/surgery , Adult , Aged , Duodenal Ulcer/complications , Follow-Up Studies , Humans , Middle Aged , Peptic Ulcer Perforation/complications , Retrospective Studies , Suture Techniques , Time Factors , Treatment OutcomeABSTRACT
Electrosurgical aseptic invaginated staple-knot suture of duodenal stump has been developed, experimentally tested on cadavers (n=8) and mongrel dogs (n=20), and successfully applied in clinical practice (n=27). In contrast to two-layer intestinal closure, this suture is characterized by less marginal necrosis of tissue and inflammation in combination with good tissue consolidation. For prophylaxis of sutures insufficiency it is also appropriate to use original method of intraintestinal decompression.
Subject(s)
Duodenum/surgery , Gastric Stump , Gastrointestinal Diseases/surgery , Postoperative Complications/prevention & control , Suture Techniques/standards , Digestive System Surgical Procedures/methods , HumansABSTRACT
Based on experiments (n=36), studies on cadavers (n=17) and clinical studies (n=462) advantages of developed electrosurgical method of creation of one-row gastroduodenal anastomosis of a closed type are shown. It heals better compared with two-row sutures. Good conditions of tissues trophicity lead to a decrease of alteration and improvement of reparative processes. Clinical studies demonstrated reliability of anastomosis. It provides minimal postoperative complications, including potentially fatal ones. It is easy for surgeon, doesn't require large mobilization of duodenal stump even in difficult cases.
Subject(s)
Electrosurgery/methods , Peptic Ulcer/surgery , Humans , Postoperative Complications/prevention & controlABSTRACT
The method of extraperitonization of the blind gut cupola based on the removable monofilament sutures and drainage of the area was designed, approved in experiments in dogs (n=18) and corpses (n=14) and successfully applied in the clinic (n=25). Unlike the traditional method, the using of this one results in less impaired trophicity, LPO intensification and phospholipase activity of the tissues of regenerating structures that was the grounds of sufficiently rapid reparation process under conditions of inflammation. The proposed complex of surgical measures in patients with destructive forms of acute appendicitis complicated by the inflammatory-necrotic phenomena in the blind gut wall was shown to prevent the development of dangerous postoperative complications, incompetence of the sutures included.