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Fiziol Zh (1994) ; 48(1): 30-4, 2002.
Article in Ukrainian | MEDLINE | ID: mdl-11928629

ABSTRACT

The experiments were carried out on 36 male rats with an acute renal insufficiency--sublimate-induced nephropathy. An increased amount of both tromboxan A2, and prostaglandine F2a has been shown to play a pathogenic role in the disorders of the main energy-dependent process in kidney--reabsorbtion of sodium ions. The negative correlative relation between the concentration of sodium ions in plasma and an increased amount of prostaglandine E2 in a kidney papilla can be explained by the hyperfunction of the interstitial cells of a kidney papilla and with a natriuretic effect of prostaglandine E2 at the level of collective tubules.


Subject(s)
Acute Kidney Injury/physiopathology , Kidney/metabolism , Prostaglandins/physiology , Sodium/metabolism , Absorption , Animals , Dinoprost/physiology , Dinoprostone/physiology , Kidney/physiopathology , Kidney Medulla/metabolism , Kidney Tubules, Collecting/metabolism , Male , Rats , Thromboxane A2/physiology
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