ABSTRACT
In order to find a relationship between risk factors and the incidence of premature delivery, 3014 delivery histories, including 323 protocols of premature deliveries, have been surveyed. Study results depicted the magnitude of risk associated with determinants like maternal growth, deficient body weight, occupation, parity, a history of reproductive dysfunction. Sixteen percent of women with term and 35% with preterm deliveries were a high-risk population. The incidence of premature delivery in it was 24%, suggesting an adequate predictive value of the risk scoring system.
Subject(s)
Obstetric Labor, Premature/etiology , Pregnancy Complications/physiopathology , Adolescent , Adult , Body Weight/physiology , Female , Humans , Maternal Age , Pregnancy , Prognosis , Risk Factors , Single ParentSubject(s)
Fetal Membranes, Premature Rupture/therapy , Obstetric Labor, Premature/therapy , Adult , Combined Modality Therapy , Female , Humans , Infant Mortality , Infant, Newborn , Infant, Premature , Obstetric Labor, Premature/complications , Pregnancy , Pregnancy Trimester, Second , Pregnancy Trimester, Third , Puerperal Infection/epidemiology , RiskSubject(s)
Abortion, Threatened/drug therapy , Abortion, Threatened/etiology , Adrenal Hyperplasia, Congenital/drug therapy , Allylestrenol/administration & dosage , Drug Evaluation , Drug Therapy, Combination , Ethinyl Estradiol/administration & dosage , Female , Humans , Hypogonadism/drug therapy , Prednisolone/administration & dosage , PregnancyABSTRACT
Endometrium obtained during menses from 46 healthy women in reproductive age was investigated morphologically and cytospectrophotometrically in order to solve the problem on the source of the cells reepithelizing the uterine mucous membrane after desquamation. It was stated that desquamation takes place not in the whole functional layer of endometrium, some mucous fragments, covered with persisting luminal epithelium, are always preserved. During endometrial regeneration the cells of the luminal and glandular epithelia and those of endometrial stroma are predominantly diploid. The amount of premitotic cells in population is so small that they cannot secure any intensive cellular proliferation. Mitogenesis in endometrium is stimulated only after a complete restoration of the epithelial layer. It is suggested that persisting luminal epithelium is the source of cells for reepithelization; they migrate towards endometrial "wounds" and repair defects in the uterine mucosa during the regeneration phase.
Subject(s)
DNA/analysis , Endometrium/cytology , Menstruation , Mitosis , Adult , Biopsy , Cell Nucleus/analysis , Female , Humans , Photometry , Time FactorsSubject(s)
Endometrium/anatomy & histology , Menstruation , Adult , Endometrium/metabolism , Female , Humans , Time FactorsABSTRACT
DNA content in the endometrial gland cells (9 women of fertile age) was studied during menstruation by microspectrophotometry. It was shown that DNA content (mainly 2n) remained unchanged during different days of menstruation, both during the desquamation (the 1st--2nd days of the cycle), and during the regeneration stage (the 3rd--4th days). Along with this the mitotic activity in the glandular epithelium was absent completely (36 samples of endometrium).
