[Transcapillary fluid exchange in the heart infused with increasing doses of noradrenaline]. / Transkapilliarnyi obmen zhidkosti v serdtse pri infuzii vozrastaiushchikh doz noradrenalina.

The velocity of transcapillary shift of fluid in the heart, the resistance against blood flow in the heart arterial and venous vessels, the capillary filtration coefficient were assessed in the cat isolated heart perfused with a donor--cat blood. The capillary hydrostatic pressure, at 0 and 10 mm Hg venous pressure in the heart, was 5.1 +/- 1.2 and 16.3 +/- 2.8 mm Hg, resp. Infusion of noradrenaline lowered the capillary hydrostatic pressure. The average capillary filtration coefficient was 0.22 +/- 0.03 ml/min/100 g/mm Hg in the heart and did not depend on the venous pressure. Noradrenaline increased the coefficient.

[Macro- and microhemodynamics and transcapillary fluid exchange in skeletal muscle and the intestines after intra-arterial injection of obsidan and corinfar]. / Makro- i mikrogemodinamika, transkapilliarnyi obmen zhidkosti v skeletnoi myshtse i kishechnike pri vnutriarterial'nom vvedenii obzidana i korinfara.

In the cat autoperfused and hemodynamically isolated m. gastrocnemius and small intestine, i.a. infusion of corinphare enlarged arterial vessels in both organs, increased venous outflow in the muscle and altered it in the intestine, decreased pre- and postcapillary resistance as well as hydrostatic pressure in both organs which led to absorption of fluid from the interstitium and increased the capillary filtration coefficient (CFC). Administration of obsidan into the skeletal muscle vascular bed induced a decrease of the perfusion pressure and precapillary resistance whereas its infusion into the intestine entailed both analogous and contrary changes of these parameters. Obsidan reduced venous outflow, increased the CFC, postcapillary resistance and capillary hydrostatic pressure, thus entailing a fluid filtration into the interstitial space.