Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
BMJ Case Rep ; 20162016 Aug 03.
Article in English | MEDLINE | ID: mdl-27489063

ABSTRACT

Clostridium sordellii is a spore-forming anaerobic Gram-positive rod that has rarely been reported to cause disease in humans. Resultant mortality from infection is estimated at nearly 70% and is most often correlated with gynaecological procedures, intravenous drug abuse or trauma. C. sordellii infection often presents similarly to toxic shock syndrome (TSS); notable features of infection include refractory hypotension, haemoconcentration and marked leucocytosis. Although clinically similar to TSS, a notable difference is C. sordellii infections rarely involve fever. The organism's major toxins include haemorrhagic (TcsH) and lethal factor (TcsL), which function to disrupt cytoskeletal integrity. Current literature suggests treating C. sordelli infection with a broad-spectrum penicillin, metronidazole and clindamycin. We present a case of C. sordellii bacteraemia and septic shock in an immunocompromised patient who was recently diagnosed with pleomorphic gluteal sarcoma. Despite presenting in critical condition, the patient improved after aggressive hemodynamic resuscitation, source control and intravenous antibiotic therapy.


Subject(s)
Bacteremia/diagnosis , Clostridium Infections/diagnosis , Clostridium sordellii , Immunocompromised Host , Liposarcoma/microbiology , Aged , Anti-Bacterial Agents/administration & dosage , Bacteremia/drug therapy , Bacteremia/microbiology , Clostridium Infections/drug therapy , Clostridium Infections/microbiology , Diagnosis, Differential , Female , Humans , Shock, Septic
SELECTION OF CITATIONS
SEARCH DETAIL
...