1.
Angew Chem Int Ed Engl
; 55(23): 6689-93, 2016 06 01.
Article
in English
| MEDLINE
| ID: mdl-27088754
ABSTRACT
A practical and highly stereoselective iron-catalyzed cross-coupling reaction of stereodefined enol carbamates and Grignard reagents to yield tri- and tetrasubstituted acrylates is reported. A facile method for the stereoselective generation of these enol carbamates has also been developed.
Subject(s)
Carbamates/chemistry , Iron/chemistry , Acrylates/chemistry , Catalysis , Magnetic Resonance Spectroscopy , Stereoisomerism
2.
J Org Chem
; 76(15): 5915-23, 2011 Aug 05.
Article
in English
| MEDLINE
| ID: mdl-21682322
ABSTRACT
The synthesis of 3,4,5-trisubstituted pyrazoles via a tandem catalytic cross-coupling/electrocyclization of enol triflates and diazoacetates is presented. The initial scope of this methodology is demonstrated on a range of differentially substituted acyclic and cyclic enol triflates as well as an elaborated set of diazoacetates to provide the corresponding pyrazoles with a high degree of structural complexity.
